LOXO-101

  • Alternative_Names
    ARRY-470;Larotrectinib
  • CAS
    1223403-58-4
  • MWt
    428.44
  • Formula
    C21H22F2N6O2
  • Solubility
    DMSO: ≥ 4.6 mg/mL
  • Clinical_Information
    Phase 2
  • Pathway
    Protein Tyrosine Kinase/RTK
  • Target
    Trk Receptor
  • Gene target
  • Gene symbol
    MIR101-2, MIR101-1, DERL2
  • Short name
    LOXO-101
  • Alternative name
    LOXO-101
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note:The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
  • Tree numbers
    • E05.393.220
  • Qualifiers
    drug effects, methods, radiation effects
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