GSK-LSD1 Dihydrochloride

  • Alternative_Names
    NA
  • CAS
    2102933-95-7
  • MWt
    289.24
  • Formula
    C14H22Cl2N2
  • Solubility
    DMSO: ≥100 mg/mL
  • Clinical_Information
    No Development Reported
  • Pathway
    Epigenetics;Neuronal Signaling
  • Target
    Histone Demethylase;Monoamine Oxidase
  • Datasheet
    NA
  • SDS
    NA
  • Gene
    Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
  • Gene target
  • Gene symbol
    KDM1A
  • Short name
    GSK-LSD1 Dihydrochloride
  • Alternative name
    GSK-LSD1 Dihydrochloride
Gene info
Similar products
Filters
+32-(0)1-658-90-45 [email protected]
GSK LSD1 Dihydrochloride - Gentaur.com
Contact
Chat with gentaur.com employee