E3 Ligase Ligand-Linker Conjugates 2

  • Alternative_Names
    NA
  • CAS
    1818885-63-0
  • MWt
    540.57
  • Formula
    C27H32N4O8
  • Solubility
    DMSO
  • Clinical_Information
    No Development Reported
  • Pathway
    PROTAC
  • Target
    E3 Ligase Ligand-Linker Conjugate
  • Description
    FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
MeSH Data
  • Name
  • Concept
    Scope note:A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
  • Tree numbers
    • E05.393.620.311
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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