AF-353

• Catalog number
  HY-14483
• Price
  Please ask
• Size
  50mg

• Alternative_Names
  Ro-4
• CAS
  865305-30-2
• MWt
  400.21
• Formula
  C14H17IN4O2
• Solubility
  DMSO: ≥ 32 mg/mL
• Clinical_Information
  No Development Reported
• Pathway
  Membrane Transporter/Ion Channel
• Target
  P2X Receptor
• Datasheet
• SDS

• Gene target
  AF-353  
• Gene symbol
  PSMD4, MLLT3, AFDN, EPS15, IFNGR2, AFF1
• Short name
  AF-353
• Alternative name
  AF-353

Gene info

• Identity
  HGNC:9561
• Gene
  PSMD4
• Long gene name
  proteasome 26S subunit ubiquitin receptor, non-ATPase 4
• Synonyms gene name
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
  • proteasome 26S subunit, non-ATPase 4
• Synonyms
  • S5A
  • AF-1
  • AF
  • Rpn10
• GenBank acession
  • U51007
• Locus
  1q21.3
• Discovery year
  1995-11-28
• Entrez gene record
  5710
• Pubmed identfication
  • 8641424
• RefSeq identity
  • NM_002810
• Classification
  • Proteasome
• VEGA ID
  OTTHUMG00000012349

Gene info

• Identity
  HGNC:7136
• Gene
  MLLT3
• Long gene name
  MLLT3 super elongation complex subunit
• Synonyms gene name
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
• Synonyms
  • AF-9
  • AF9
  • YEATS3
• GenBank acession
  • L13744
• Locus
  9p21.3
• Discovery year
  1993-04-08
• Entrez gene record
  4300
• Pubmed identfication
  • 8506309
  • 8414510
• RefSeq identity
  • NM_004529
• Classification
  • MicroRNA protein coding host genes
  • Super elongation complex
  • YEATS domain containing
• VEGA ID
  OTTHUMG00000019650

Gene info

• Identity
  HGNC:7137
• Gene
  AFDN
• Long gene name
  afadin, adherens junction formation factor
• Synonyms gene
  • MLLT4
• Synonyms gene name
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4
• Synonyms
  • AF-6
  • AF6
• GenBank acession
  • AB011399
• Locus
  6q27
• Discovery year
  1994-09-06
• Entrez gene record
  4301
• Pubmed identfication
  • 8242616
• RefSeq identity
  • NM_005936
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000016031

Gene info

• Identity
  HGNC:3419
• Gene
  EPS15
• Long gene name
  epidermal growth factor receptor pathway substrate 15
• Synonyms
  • AF-1P
  • MLLT5
• GenBank acession
  • BC054006
• Locus
  1p32.3
• Discovery year
  1994-12-19
• Entrez gene record
  2060
• Pubmed identfication
  • 8183552
• RefSeq identity
  • NM_001981
• Classification
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000008192

Gene info

• Identity
  HGNC:5440
• Gene
  IFNGR2
• Long gene name
  interferon gamma receptor 2
• Synonyms gene
  • IFNGT1
• Synonyms gene name
  • interferon gamma receptor 2 (interferon gamma transducer 1)
• Synonyms
  • AF-1
• Locus
  21q22.11
• Discovery year
  1986-01-01
• Entrez gene record
  3460
• Pubmed identfication
  • 3136170
• Classification
  • Interferon receptors
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000065188
• Locus Specific Databases
  • IFNGR2base: Mutation registry for IFNγ2-receptor deficiency
  • LRG_67

Gene info

• Identity
  HGNC:7135
• Gene
  AFF1
• Long gene name
  AF4/FMR2 family member 1
• Synonyms gene
  • PBM1
  • MLLT2
• Synonyms gene name
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 2
  • pre-B-cell monocytic leukemia partner 1
  • AF4/FMR2 family, member 1
• Synonyms
  • AF-4
  • AF4
• GenBank acession
  • L22179
• Locus
  4q21.3-q22.1
• Discovery year
  2005-06-27
• Entrez gene record
  4299
• Pubmed identfication
  • 7689231
  • 1423625
  • 8353274
• RefSeq identity
  • NM_005935
• Classification
  • Super elongation complex
  • AF4/FMR2 family
• VEGA ID
  OTTHUMG00000130603

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