Human Hepatitis A virus cellular receptor 2 (HAVCR2) -E. coli

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• Catalog number
  GEN1265286.E.coli
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• Size
  1000ug

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• Long name
  Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2)
• Alternative names
  hepatitis A virus cellular receptor 2; Hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2; kidney injury molecule-3; T-cell membrane protein 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin mucin receptor 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin and mucin domain-containing protein 3; hepatitis A virus cellular receptor 2; T-cell immunoglobulin and mucin domain-containing protein 3; TIMD-3; T-cell immunoglobulin mucin receptor 3; TIM-3; T-cell membrane protein 3
• Gene name
  HAVCR2
• Other gene names
  HAVCR2; HAVCR2; TIM3; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2; TIM3; TIMD3; HAVcr-2; TIMD-3; TIM-3
• General description
  Hepatitis A virus cellular receptor 2(HAVCR2) is a recombinant protein expressed in E. coli. The protein can be with or without a His-Tag or other tag in accordance to customer's request. All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility.
• Product category
  Recombinant Proteins
• Expression system
  E. coli
• Available also expressed in
  E Coli ; Yeast ; Baculovirus ; Mammalian Cell
• Purity
  Greater than 90% (determined by SDS-PAGE)
• Form
  Lyophilized protein
• Storage
  This protein can be stored at -20 degrees Celsius. For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius. Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains.
• Applications
  This protein can be used as a positive control for applications such as ELISA, IFA, RIA, Western Blot, etc.
• Description
  Hepatitis a, b, c, d, e recombinant surface viral antigens to genotype 1, 2, 3, 4, 5 are used for antibody production to make diagnostic poly or monoclonal antibodies. Hepatitis is a disease of the liver characterized by the presence of inflammatory cells in the tissue of the organ. Hepatitis may occur without symptoms, but can lead to jaundice (a yellow discoloration of the skin, mucous membranes, and conjunctiva of the eyes), poor appetite, and fatigue. Depending on the cause, hepatitis can manifest either as an acute or as a chronic disease. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

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• Gene target
  Hepatitis   virus   cellular   receptor   HAVCR2  
• Gene symbol
  HAVCR2
• Short name
  Hepatitis A virus cellular receptor 2(HAVCR2)
• Technique
  cellular
• Host
  e. coli, Escherichia coli, Recombination of bioactive proteins and longer peptides in Escherichia Coli is done often with His tagging. MBS Recombinant supplies Rec. E. Coli affinity purified or tag purified antigens in 1 quantities or bulk volumes on request.
• Species
  E. coli, E. coli, Humans, Viruses
• Alternative name
  H. sapiens Hepatitis A virus cellular receptor 2 (hepatitis A virus cellular receptor 2) -E. coli
• Alternative technique
  escherichia
• Alternative to gene target
  hepatitis A virus cellular receptor 2, HAVCR2 and IDBG-55271 and ENSG00000135077 and 84868, protein binding, Plasma membranes, Havcr2 and IDBG-165782 and ENSMUSG00000020399 and 171285
• Tissue
  cellular
• Virus
  hepatitis

Gene info

• Identity
  HGNC:18437
• Gene
  HAVCR2
• Long gene name
  hepatitis A virus cellular receptor 2
• Synonyms
  • Tim-3
  • TIM3
  • FLJ14428
  • TIMD3
  • CD366
• Synonyms name
  • T-cell immunoglobulin mucin family member 3
• GenBank acession
  • AK027334
• Locus
  5q33.3
• Discovery year
  2002-12-04
• Entrez gene record
  84868
• Pubmed identfication
  • 11823861
• RefSeq identity
  • NM_032782
• Classification
  • V-set domain containing
• VEGA ID
  OTTHUMG00000130249

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