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Alternative name1
Anti-RABBIT ANTI HUMAN PARATHYROID HORMONE RELATED PEPTIDE
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Alternative name2
RABBIT ANTI HUMAN PARATHYROID HORMONE RELATED PEPTIDE
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Alternative name3
Lapin ANTI Homo sapiens PARattus norvegicusHYROID HORMONE RELATED PEPTIDE
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Alternative name4
PARATHYROID HORMONE RELATED PEPTIDE
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Alternative name5
N/A
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Other names
parathyroid hormone-related protein isoform 2 preproprotein; Parathyroid hormone-related protein; parathyroid hormone-related protein; PTH-rP; osteostatin; PTH-related protein; parathyroid hormone-like related protein; parathyroid hormone-related protein preproprotein; parathyroid hormone-like hormone; Parathyroid hormone-like protein; PLPCleaved into the following 3 chains:PTHrP[1-36]PTHrP[38-94]Osteostatin; Alternative name(s):; PTHrP[107-139]
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Gene name
N/A
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Gene name synonims
N/A
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Other gene names
PTHLH; PTHLH; HHM; PLP; BDE2; PTHR; PTHRP; PTHRP; PTH-rP; PTHrP; PLP
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
Polyclonal IgG
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Clone
Polyclonal antibody
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Host organism
Rabbit
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Species reactivity
Human
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Specificity and cross reactivity
PARATHYROID HORMONE RELATED PEPTIDE This item specifically recognises human Parathyroid hormone related peptide (PTHrP), a ubiquitously produced neuroendocrine polypeptide hormone, which signals through Parathyroid Hormone Receptor 1 (PTHR1), and acts as a critical regulator of cellular and tissue development, cell differentiation and migration, calcium and phosphorous extracellular concentrations, bone, teeth, and mammary gland development, and epithelial calcium ion transport. Studies have shown the involvement of PTHrP during the metastasis of colon cancer cells, identifying a positive correlation between PTHrP, Rac1 activity, the guanine nucleotide exchange factor Tiam1, and integrin alpha6beta4. Elevated expression of PTHrP is most commonly associated with breast cancer, and also with gastrointestinal (GI) tumours.
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Purification method
N/A
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Form Appearance
Purified (Purified IgG - lyophilised)
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Concentration
IgG concentration 1.0mg/ml after reconstitution
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Storage and shipping
Prior to reconstitution store at +Store productone at +4 degrees Celsius.. After reconstitution For optimal long term storage, productone should be kept at -20 degrees Celsius. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.
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Tested for
Western Blot (WB), ELISA (EIA)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Hormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
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Test
MBS Polyclonals supplies antibodies that are for research of human proteins.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
