TLR8 (Toll Like Receptor 8, Toll-like Receptor 8, TLR 8, CD288, CD288 Antigen, MGC119599, MGC119600) (FITC) Antibody
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Catalog number
GEN604865
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Price
Please ask
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Size
100ug
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Also known as
TLR8
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Other names
TLR8; N/A
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
N/A
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Gene name synonims
N/A
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Other gene names
N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
6D83
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Host organism
Mouse (Mus musculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes human TLR8 at ~120kD. Species Crossreactivity: mouse.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Affinity Purified by Protein G affinity chromatography.
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Form Appearance
Supplied as a liquid in PBS pH7.2, 50% glycerol. Labeled with fluorescein isothiocyanate (FITC).
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
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Tested applications
Western Blot (WB), Flow Cytometry (FC/FACS)
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This MBS Monoclonals Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MBS Monoclonals FITC is highly sensitive to pH extremes.
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Description
Antigens are peptides or recombinant or native dependent on the production method. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Conjugation
Anti-FITC Antibody
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French translation
anticorps
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Gene target
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Gene symbol
TLR8, TLR8-AS1, TLR4
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Short name
TLR8 (Toll Like Receptor 8, Toll-like Receptor 8, TLR 8, CD288, CD288 Antigen, MGC119599, MGC119600) (FITC) Antibody
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Technique
Antibody, antigen, FITC, antibodies against human proteins, antibodies for, antigenes, Fluorescein
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Label
FITC
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Alternative name
Anti-TLR8 (Toll Like Receptor 8, Toll-like Receptor 8, TLR 8, CD288, CD288 Antigen, MGC119599, MGC119600) (FITC)
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Alternative technique
antibodies, antigenes, fluorescine
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Alternative to gene target
toll-like receptor 8, TLR8 and IDBG-44288 and ENSG00000101916 and 51311, drug binding, Plasma membranes, Tlr8 and IDBG-185523 and ENSMUSG00000040522 and 170744
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Gene info
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Identity
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Gene
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Long gene name
toll like receptor 8
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-04-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Toll like receptors
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
TLR8 antisense RNA 1
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Synonyms gene name
- TLR8 antisense RNA 1 (non-protein coding)
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Locus
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Discovery year
2011-07-29
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Entrez gene record
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
toll like receptor 4
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-06-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Toll like receptors
- CD molecules
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
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Tree numbers
- E01.370.225.500.386
- E05.196.712.516.600.240
- E05.200.500.386
- E05.242.386
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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