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Also known as
NKp46, Natural Cytotoxicity Receptor
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Other names
natural cytotoxicity triggering receptor 1 isoform a; Natural cytotoxicity triggering receptor 1; natural cytotoxicity triggering receptor 1; NK cell-activating receptor; natural killer cell p46-related protein; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
NCR1; NCR1; LY94; CD335; NKP46; NK-p46; LY94; NK-p46; NKp46; hNKp46
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Gene name synonims
NCR1; NCR1; LY94; CD335; NKP46; NK-p46; LY94; NK-p46; NKp46; hNKp46
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Other gene names
NCR1; NCR1; LY94; CD335; NKP46; NK-p46; LY94; NK-p46; NKp46; hNKp46
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1,k
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Clone
4k12
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Host organism
Mouse (Mus musculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes human NKp46.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Affinity Purified from mouse ascitic fluid by Protein G affinity chromatography.
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Form Appearance
Supplied as a liquid in PBS, pH 7.4 and 0.08% sodium azide.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store the antibody should be stored at -20 degrees Celsius. or colder. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
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Tested applications
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
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Description
For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
