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Also known as
CD180
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Other names
CD180 antigen; CD180 antigen; CD180 antigen; lymphocyte antigen 64; radioprotective 105 kDa protein; lymphocyte antigen-64, radioprotective, 105kDa; CD180 molecule; Lymphocyte antigen 64; Radioprotective 105 kDa protein
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
CD180
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Gene name synonims
N/A
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Other gene names
CD180; CD180; LY64; Ly78; RP105; LY64; RP105
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
MHR73
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
CD180 Recognises human CD180 (RP105) a 105kD type 1 transmembrane protein, which belongs to the toll-like receptor family. CD180 is primarily expressed in mature peripheral B cells and is thought to play a role in the innate immune response to bacterial lipopolysaccharide, through co-operation with MD-1 and TLR4. _x000D__x000D_Cross linking of CD180 with clone MHR73 has been reported to induce resistance against irradiation induced apoptosis, B-cell proliferation and up-regulation of a co-stimulatory molecule CD80. Removal of sodium azide is recommended prior to use in functional studies.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
Purified (Purified IgG - liquid)
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Concentration
IgG concentration 0.5 mg/ml
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Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term. the antibody should be stored undiluted. Storage in frost-free freezers is not recommended. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
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Tested applications
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistology - Frozen (IHC)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Test
MBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps
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Gene target
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Gene symbol
CD180
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Short name
MOUSE Anti- CD180 Antibody
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Technique
anti-Human, Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, mouses
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Host
mouse
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Species
Human, Humans, Mouses
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Alternative name
Anti-MOUSE ANTI HUMAN CD180
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Alternative technique
antibodies, murine
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Alternative to gene target
CD180 molecule, LY64 and Ly78 and RP105, CD180 and IDBG-24968 and ENSG00000134061 and 4064, protein binding, Plasma membranes, Cd180 and IDBG-179053 and ENSMUSG00000021624 and 17079, BT.22214 and IDBG-628694 and ENSBTAG00000006360 and 539518
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