Monoclonal mouse anti- thrombin activatable fibrinolysis inhibitor (TAFI)

• Catalog number
  GEN660037
• Price
  Please ask
• Size
  1000ug

• Also known as
  TAFI
• Other names
  thrombin-activatable fibrinolysis inhibitor; Carboxypeptidase B2; carboxypeptidase B2; carboxypeptidase R; carboxypeptidase U; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor; carboxypeptidase B2 (plasma); Carboxypeptidase R; CPR; Carboxypeptidase U; CPU; Thrombin-activable fibrinolysis inhibitor; TAFI
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  TAFI
• Gene name synonims
  N/A
• Other gene names
  Cpb2; Cpb2; CPR; Cpu; TAFI; AI255929; 1110032P04Rik; 4930405E17Rik; Tafi; CPR; CPU; TAFI
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1 for MAbs 13H4 and 19E2 IgG2a for MAb 13D5
• Clone
  13D5, 13H4, 19E2
• Host organism
  N/A
• Species reactivity
  N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Human TAFI; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Chromatography on protein A Sepharose
• Form Appearance
  PBS, pH 7.4, 0.1 % sodium azide (NaN3)
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius.
• Tested applications
  N/A
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Monoclonal   thrombin   activatable   fibrinolysis   inhibitor   TAFI  
• Gene symbol
  CPB2
• Short name
  Monoclonal mouse anti- thrombin activatable fibrinolysis inhibitor (TAFI)
• Technique
  Mouse, anti, antibody to, Monoclonals or monoclonal antibodies, mouses
• Host
  mouse
• Species
  Mouse, Mouses
• Alternative name
  Anti-Monoclonal mouse anti- thrombin activatable fibrinolysis inhibitor (TAFI)
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:2300
• Gene
  CPB2
• Long gene name
  carboxypeptidase B2
• Synonyms gene name
  • carboxypeptidase B2 (plasma, carboxypeptidase U)
  • carboxypeptidase B2 (plasma)
• Synonyms
  • CPU
  • PCPB
  • TAFI
• Synonyms name
  • thrombin-activatable fibrinolysis inhibitor
  • carboxypeptidase U
  • plasma carboxypeptidase B
  • carboxypeptidase R
• GenBank acession
  • M75106
• Locus
  13q14.13
• Discovery year
  1992-04-10
• Entrez gene record
  1361
• Pubmed identfication
  • 1939207
  • 1427879
• RefSeq identity
  • NM_001872
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000016867
• Locus Specific Databases
  • LRG_632

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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