TRAIL protein

Category

Proteins
Antibody Subtype

Recombinant Proteins
Area of research

Cell Cycle & Cell Death
Reactivity

Human
Residues

Region of TRAIL protein corresponding to amino acids MRERGPQRVA AHITGTRGRS NTLSSPNSKN EKALGRKINS WESSRSGHSF LSNLHLRNGE LVIHEKGFYY IYSQTYFRFQ EEIKENTKND KQMVQYIYKY TSYPDPILLM KSARNSCWSK DAEYGLYSIY QGGIFELKEN DRIFVSVTNE HLIDMDHEAS FFGAFLVG.
Type of protein

Recombinant
Expression System

Escherichia coli
Grade Purity

Grater than 98% pure
Form Buffer

Lyophilized from 10 mM Na3PO4, pH 7.2, with 110 mM NaCl. Reconstitute with water to 0.5-1.0 mg/ml .
Storage

Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Shipping conditions

Blue Ice
Tested for

Please refer to the datasheet
Bioactivity

Assay#1:Determined by its ability to induce apoptotic cell death in TRAIL-sensitive U343MG cells. The expected ED50 for this effect is 1.0-3.0 ng/ml. Assay#2:Measured by its ability to induce apoptosis in LN-18 cells (human glioblastoma cells). The expected ED50 for this effect is 0.8 - 2.0 ng/ml.
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