TEM8 (Tumor Endothelial Marker 8, Bacillus anthracis (Anthrax) Toxin Receptor, ATR1)

• Catalog number
  GEN603164
• Price
  Please ask
• Size
  100ug

• Also known as
  TEM8
• Other names
  tumor endothelial marker 8; Anthrax toxin receptor 1; anthrax toxin receptor 1; 2310008J16Rik; 2810405N18Rik; tumor endothelial marker 8; anthrax toxin receptor 1; Tumor endothelial marker 8
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  ANTXR1; ANTXR1; ATR; TEM8; FLJ10601; FLJ11298; FLJ21776; ANTXR1; ATR; TEM8
• Gene name synonims
  ANTXR1; ANTXR1; ATR; TEM8; FLJ10601; FLJ11298; FLJ21776; ANTXR1; ATR; TEM8
• Other gene names
  ANTXR1; ANTXR1; ATR; TEM8; FLJ10601; FLJ11298; FLJ21776; ANTXR1; ATR; TEM8
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2b
• Clone
  7H149
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Selected for its ability to detect human TEM8 in direct ELISAs and Western Blots.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography.
• Form Appearance
  Supplied as a lyophilized powder from a 0.2um filtered solution in PBS with 5% trehalose. Reconstitute with sterile PBS, 40-50% glycerol. If 0.2ml is used, the concentration will be 0.5mg/ml.
• Concentration
  N/A
• Storage and shipping
  Lyophilized powder Store the antibody at +4 degrees Celsius for short term storage.. Reconstitute to nominal volume by adding sterile PBS with 40-50% glycerol and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  ELISA (EL/EIA), Western Blot (WB)
• Description
  Bacillus Anthracis and Cereus are the most known Bacilli. Anthrax has a very high toxin level and is used in Biologic warfare. However 1 is a harmless product. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  TEM8   Tumor   Endothelial   Bacillus   anthracis   Anthrax   Receptor   ATR1  
• Gene symbol
  ANTXR1, SLC3A1
• Short name
  TEM8 (Tumor Endothelial 8, Bacillus anthracis (Anthrax) Receptor, ATR1)
• Technique
  Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA.
• Alternative name
  Anti-TEM8 (Tumor Endothelial Marker 8, Bacillus anthracis (Anthrax) Toxin Receptor, ATR1)
• Tissue
  tumor

Gene info

• Identity
  HGNC:21014
• Gene
  ANTXR1
• Long gene name
  ANTXR cell adhesion molecule 1
• Synonyms gene name
  • anthrax toxin receptor 1
• Synonyms
  • TEM8
  • FLJ21776
  • FLJ10601
  • ATR
• Synonyms name
  • anthrax toxin receptor
  • tumor endothelial marker 8 precursor
• GenBank acession
  • AF421380
• Locus
  2p13.3
• Discovery year
  2003-08-27
• Entrez gene record
  84168
• Pubmed identfication
  • 10947988
  • 11559528
• RefSeq identity
  • NM_032208
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000129575

Gene info

• Identity
  HGNC:11025
• Gene
  SLC3A1
• Long gene name
  solute carrier family 3 member 1
• Synonyms gene name
  • solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1
  • solute carrier family 3 (amino acid transporter heavy chain), member 1
• Synonyms
  • CSNU1
  • D2H
  • RBAT
  • ATR1
  • NBAT
• Locus
  2p21
• Discovery year
  1993-12-16
• Entrez gene record
  6519
• Pubmed identfication
  • 8486766
  • 9186880
• RefSeq identity
  • NM_000341
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000128759

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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