Specific Intracellular Adhesion Molecule Grabbing Nonintegrin R1 (SIGN-R1)
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Catalog numberGEN604030
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PricePlease ask
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Size0.25 miligrams
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Also known asSpecific Intracellular Adhesion Molecule Grabbing Nonintegrin R1
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Other namesN/A
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesN/A
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ClonalityMonoclonal
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Immunoglobulin isotypeIgM
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Clone8J189
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Host organismRat (Rattus norvegicus)
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Source organismMouse (Mus musculus)
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Species reactivityMouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes mouse SIGN-R1, a C-type lectin that has been identified as a murine homolog of the human CD-SIGN related molecule, L-SIGN. Mouse SIGN-R1 is specifically expressed on marginal zone macrophages in the spleen, medullary and subcapsular sinus macrophages in the lymph nodes, and at lower levels on liver sinusoidal endothelial cells. SIGN-R1 has not been detected on murine dendritic cell populations. Blocks the uptake of neutral polysaccharides by macrophages.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodPurified by ammonium sulfate precipitation.
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Form AppearanceSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested applicationsImmunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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Descriptioncell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the Specific Intracellular Adhesion Molecule Grabbing Nonintegrin R1 (SIGN-R1). Whole adhesion and interacting molecules are present in lysates used as reference for ELISA quantification of these molecules and their subunits.
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Gene target
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Gene symbolCD209, C17orf75, CDCA7L, CNEP1R1, CXCL11, PNPLA7, PCAT6
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Short nameSpecific Intracellular Adhesion Molecule Grabbing Nonintegrin R1 (SIGN-R1)
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Techniqueintracellular
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Alternative nameAnti-Specific Intracellular Adhesion Molecule Grabbing Nonintegrin R1 (SIGN-R1)
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Gene info
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Identity
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Gene
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Long gene nameCD209 molecule
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Synonyms gene name
- CD209 antigen
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-07-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
- C-type lectin domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namechromosome 17 open reading frame 75
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-01-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecell division cycle associated 7 like
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Synonyms gene name
- cell division cycle associated 7-like
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Synonyms
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Locus
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Discovery year2005-05-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCTD nuclear envelope phosphatase 1 regulatory subunit 1
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Synonyms gene
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Synonyms gene name
- chromosome 16 open reading frame 69
- transmembrane protein 188
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-04-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-X-C motif chemokine ligand 11
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Synonyms gene
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Synonyms gene name
- small inducible cytokine subfamily B (Cys-X-Cys), member 11
- chemokine (C-X-C motif) ligand 11
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-06-23
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Entrez gene record
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Pubmed identfication
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Classification
- Chemokine ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namepatatin like phospholipase domain containing 7
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Synonyms gene
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Synonyms gene name
- chromosome 9 open reading frame 111
- patatin-like phospholipase domain containing 7
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-03-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Patatin like phospholipase domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprostate cancer associated transcript 6
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Synonyms gene
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Synonyms gene name
- KDM5B antisense RNA 1 (head to head)
- prostate cancer associated transcript 6 (non-protein coding)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2012-02-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Long non-coding RNAs with non-systematic symbols
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VEGA ID