Rabbit Anti Simian immunodeficiency virus vpx Antibody-HRP

  • Catalog number
    CSB-PA320847HB01SHA_50ug
  • Price
    Please ask
  • Size
    50ug
  • Long name
    Rabbit Antibody against Simian immunodeficiency virus vpx, HRP
  • Synonym name
    vpx Simian immunodeficiency virus Antibody
  • Species reactivity
    Simian immunodeficiency virus
  • Tested applications recommended dilutions
    ELISA
  • Conjugation
    HRP
  • Antibody isotype
    IgG
  • UniProt ID
    P11266
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant Simian immunodeficiency virus Protein Vpx protein (1-112AA)
  • Immunogen species
    Simian immunodeficiency virus
  • Alias
    Protein Vpx,Viral protein X,X ORF protein,vpx
  • Background
    Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    vpx Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
  • Additional conjugation
    HRP Conjugated
  • About
    Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
  • Latin name
    Oryctolagus cuniculus
  • French translation
    anticorps
  • Gene target
  • Short name
    Anti-vpx
  • Technique
    Antibody, Rabbit, anti, antibody to, antibodies against human proteins, antibodies for
  • Host
    Rabbit, Rabbits
  • Label
    HRP
  • Species
    Virus, Viruses
  • Alternative name
    vpx Antibody,HRP conjugated
  • Alternative technique
    antibodies, rabbit-anti
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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