HIV reverse transcriptase (HIV-RT) - Biotinylated, Monoclonal Antibody
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Catalog number
F110M
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Price
Please ask
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Size
100µg
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Host Source
Mouse
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Clone Name
AS35
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Product Category
Infectious Agents & Disease
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Species Reactivity
n/a
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Application
Enzyme Immunoassay, Immunoprecipitation
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Immunogen
Recombinant immuno-deficiency virus reverse transcriptase (HIV- RT).
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Purification Method
Protein A/G Chromatography
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Shipping Conditions
Room Temperature
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Storage conditions
HIV reverse transcriptase (HIV-RT) - Biotinylated, Monoclonal Antibody should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
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Properties
If you buy Antibodies supplied by Exalpha they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Gene
The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome(AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. recombinant HIV 1 and 2 gag gene proteins p24, p17, p55 immunodominant epitopes and envelope glycoproteins, gp120 are used for production of diagnostic detection antibodies.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Description
Reverse transcription primers are used in PCR but in vivo reverse transcription begins when the viral particle that enters the cytoplasm of a target cell with its reverse transcriptase. The viral RNA genome enters the cytoplasm as part of a nucleoprotein complex that has not been well characterized. The process of reverse transcription generates, in the cytoplasm, a linear DNA via an intricate series of steps. This DNA is collinear with its RNA template, but it contains terminal duplications known as the long terminal repeats (LTRs) that are not present in viral RNA . Extant models for reverse transcription propose that two specialized template switches known as strand-transfer reactions or “jumps” are required to generate the LTRs.
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Goup
reverse transcription
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French translation
anticorps
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Gene target
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Gene symbol
HIVEP2, SNRPN
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Short name
HIV reverse transcriptase (HIV-RT) - Biotinylated, Monoclonal Antibody
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Technique
Antibody, reverse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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Isotype
IgG1
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Alternative name
human immunodeficiency virus reverse transcriptase (human immunodeficiency virus-RT) - Biotinylated, monoclonal (antibody to-)
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Alternative technique
antibodies, transctription
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Virus
hiv
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Gene info
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Identity
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Gene
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Long gene name
HIVEP zinc finger 2
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Synonyms gene name
- human immunodeficiency virus type I enhancer-binding protein 2
- human immunodeficiency virus type I enhancer binding protein 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1992-10-21
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Entrez gene record
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Pubmed identfication
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Classification
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
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Tree numbers
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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