Anti-NFKB Repressing Factor (NKRF)-Rabbit polyclonal Antibody
-
Catalog numberPAH536Hu01
-
PricePlease ask
-
Size10ug
-
-
Organism SpeciesHomo sapiens (Human)
-
SourcePolyclonal antibody preparation
-
PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
-
Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
-
Item NameNFKB Repressing Factor
-
ImmunogenRPH536Hu01-Recombinant NFKB Repressing Factor (NKRF)
-
Image number3
-
Species reactivityHuman
-
Sequence of immunogenNKRF (Met1~Val296)
-
AplicationWB,IHC
-
ClonalityRabbit polyclonal
-
Concentration500ug/ml
-
Alternative NamesITBA4; NRF; NF-Kappa B Repressing Factor; Transcription factor NRF
-
Applicable Secondary AntibodySAA544Rb59, SAA544Rb58, SAA544Rb57, SAA544Rb18, SAA544Rb19
-
Delivery condition4℃ with ice bags
-
Storage instructionsAvoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
-
PropertiesIf you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
GeneNF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
-
GroupPolyclonals and antibodies
-
AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by Cloud Clone Corp. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cloud Clone Corp adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin nameOryctolagus cuniculus
-
French translationanticorps
-
Gene target
-
Gene symbolNKRF, NFKB1
-
Short nameAnti-NFKB Repressing Factor (NKRF)-Rabbit polyclonal Antibody
-
TechniquePolyclonal, Antibody, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
HostRabbit, Rabbits
-
Alternative nameAntibody toNFKB Repressing Factor (NKRF)-production species: rabbit polyclonal (antibody to-)
-
Alternative techniquepolyclonals, antibodies, rabbit-anti
-
Gene info
-
Identity
-
Gene
-
Long gene nameNFKB repressing factor
-
Synonyms gene name
- NF-kappaB repressing factor
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2004-11-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- G-patch domain containing
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene namenuclear factor kappa B subunit 1
-
Synonyms gene name
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1991-11-14
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- NF-kappa B complex subunits
- Ankyrin repeat domain containing
- IPT domain containing
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data