Leukemia Inhibitory Factor (LIF)

• Catalog number
  GEN600410
• Price
  Please ask
• Size
  100ug

• Also known as
  Leukemia Inhibitory Factor
• Other names
  leukemia inhibitory factor; Leukemia inhibitory factor; leukemia inhibitory factor; MLPLI; D factor; OTTHUMP00000198698; human interleukin in DA cells; melanoma-derived LPL inhibitor; differentiation-inducing factor; hepatocyte-stimulating factor III; cholinergic differentiation factor; differentiation stimulating factor; differentiation-stimulating factor; differentiation inhibitory activity; leukemia inhibitory factor (cholinergic differentiation factor); Differentiation-stimulating factor; D factor; Melanoma-derived LPL inhibitor
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  LIF; LIF; CDF; DIA; HILDA; HILDA
• Gene name synonims
  LIF; LIF; CDF; DIA; HILDA; HILDA
• Other gene names
  LIF; LIF; CDF; DIA; HILDA; HILDA
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  8A317
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes recombinant human Leukemia Inhibitory Factor (LIF) and endogenous protein. Species Crossreactivity: recombinant murine LIF. No reactivity was observed with recombinant rat LIF.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.6, 0.1% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested applications
  Western Blot (WB)
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

• Gene target
  Leukemia   Inhibitory   Factor   LIF  
• Gene symbol
  LIF-AS1, LIF-AS2, LIF
• Short name
  Leukemia Inhibitory Factor (LIF)
• Alternative name
  Anti-Leukemia Inhibitory Factor (LIF)
• Alternative to gene target
  leukemia inhibitory factor, CDF and DIA and HILDA and MLPLI, LIF and IDBG-3968 and ENSG00000128342 and 3976, growth factor activity, Extracellular, Lif and IDBG-142317 and ENSMUSG00000034394 and 16878, LIF and IDBG-636335 and ENSBTAG00000007424 and 280840
• Virus
  leukemia

Gene info

• Identity
  HGNC:53473
• Gene
  LIF-AS1
• Long gene name
  LIF antisense RNA 1
• Synonyms
  • Lnc-LIF-AS
• Locus
  22q12.2
• Discovery year
  2017-04-28
• Pubmed identfication
  • 28391028
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:28298
• Gene
  LIF-AS2
• Long gene name
  LIF antisense RNA 2
• Locus
  22q12.2
• Discovery year
  2020-10-07
• Entrez gene record
  91370
• RefSeq identity
  • NR_148946
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:6596
• Gene
  LIF
• Long gene name
  LIF interleukin 6 family cytokine
• Synonyms gene name
  • leukemia inhibitory factor
  • LIF, interleukin 6 family cytokine
• Synonyms
  • CDF
  • DIA
  • HILDA
• Synonyms name
  • differentiation inhibitory activity
  • differentiation-inducing factor
  • hepatocyte-stimulating factor III
  • cholinergic differentiation factor
  • human interleukin in DA cells
• Locus
  22q12.2
• Discovery year
  1989-06-11
• Entrez gene record
  3976
• Pubmed identfication
  • 1714745
  • 8058719
• RefSeq identity
  • NM_002309
• Classification
  • Receptor ligands
  • Interleukin 6 type cytokine family
• VEGA ID
  OTTHUMG00000150910
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

MeSH Data

• Name
  Leukemia, Experimental
• Concept
  Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
• Tree numbers
  • C04.557.337.372
  • C04.619.531
  • E05.598.500.496.500
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery

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