Cyclosporine A for cell activation

  • Catalog number
    1522-1G
  • Product name
    Cyclosporine A for cell activation
  • Size
    1 g
  • Price
    322.3
  • Supplier
    Biovision
  • Description
    A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B.
  • Peptide sequence
    N/A
  • CAS number
    59865-13-3
  • Molecular weight
    1203.6
  • Category
    Biochemicals
  • Other name
    Antibiotic S 7481F1, Cyclosporine
  • Molecular formula
    C₆₂H₁₁₁N₁₁O₁₂
  • Physical appearance
    White solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    >99%
  • Reconstitute instructions
    DMSO and EtOH
  • Storage condition
    +4°C
  • Shipping condition
    RT
  • Maximum time for storage
    12 months
  • Storage instructions
    Protect from light and air
  • group_crc32
    3373553486
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    Cyclosporine A for activation
  • Technique
    activation
  • Alternative name
    Cyclosporine A to measure cellular activation
MeSH Data
  • Name
  • Concept
    Registry number:83HN0GTJ6D
    Scope note:A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).
    CASN1 number:Cyclosporin A
  • Tree numbers
    • D04.345.566.235.300
    • D12.644.641.235.300
  • Qualifiers
    immunology, pharmacokinetics, therapeutic use, toxicity, poisoning, administration & dosage, adverse effects, agonists, blood, cerebrospinal fluid, chemical synthesis, contraindications, chemistry, urine, radiation effects, history, analysis, antagonists & inhibitors, classification, economics, isolation & purification, metabolism, pharmacology, standards, supply & distribution
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