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Anti-HPV16 E6 protein (2E3) Monoclonal, ALEXA Fluor 594

  • Catalog number
    GENTObsm-0990M-A594
  • Product name
    Anti-HPV16 E6 protein (2E3) Monoclonal, ALEXA Fluor 594
  • Size
    116 microliters
  • Price
    489EUR
  • Supplier
    Bioss Monoclonal Antibodies
  • Ask
  • Clonality
    Monoclonal Antibodies
  • Conjugated with
    ALEXA FLUOR 594
  • Gene ID
    1399
  • Cross Reactive species
    Virus
  • Cross Reactive Species details
    HPV16
  • Synonyms
    E6; HPV16 E6 protein; Human Papilloma Virus; Human papillomavirus type 16 E6; Human papillomavirus type 16; Protein E6; E6 protein; HPV16 E6; HPV16-E6; VE6_HPV16.
  • Alternative name 1
    HPV16 E6 protein (2E3) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated
  • Purification method
    Purified by Protein G.
  • Advisory
    Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
  • Storage
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Target Protein/Peptide
    HPV16 E6 protein
  • Alternative name 2
    HPV16 E6 protein (2E3) Monoclonal anti-, ALEXA FLUOR 594 Conjugated
  • Modification
    Not modified
  • Host organism
    Mouse (Mus musculus)
  • Background information
    Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.
  • Specificity
    Highly specific antibody against HPV16 E6 protein
  • Applications with corresponding dilutions
    IF(IHC-P)(1:50-200)
  • Clone
    2E3
  • Applications
    IF(IHC-P)
  • Concentration
    1ug per 1ul
  • Type
    Conjugated Primary Antibody
  • Excitation emission
    590nm/617nm
  • Antigen Source
    KLH conjugated synthetic peptide derived from HPV16 E6 protein
  • Properties
    For facs or microscopy Alexa 1 conjugate.
  • Conjugation
    Alexa Fluor
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
  • Gene target
  • Short name
    Anti-HPV16 E6 protein (2E3) Monoclonal, Fluor 594
  • Technique
    Monoclonals or monoclonal antibodies
  • Label
    ALEXA
  • Alternative name
    antibody to-HPV16 E6 protein (2E3) monoclonal, ALEXA Fluor 594
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MESH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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