Activin B Recombinant Protein

  • Catalog number
    40-214
  • Price
    Please ask
  • Size
    0.001 mg, 0.005 mg
  • About recombinant protein
    Activin B is a TGF-β family member that exhibits a wide range of biological activities including regulation of embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands. Activin B, like certain other members of the TGF-β family, signals through the ActRII receptor (Activin Receptor type II). Human Activin B is a 25.6 kDa disulfide-linked homodimer consisting of two βB chains, each containing 115 amino acid residues.
  • Other name of the recombinant
    Inhibin beta B chain, Activin beta-B chain
  • Recombinant in
    (BTI-Tn-5B1-4) High-5 Insect cells
  • SEQUENCE
    GLECDGRTNL CCRQQFFIDF RLIGWNDWII APTGYYGNYC EGSCPAYLAG VPGSASSFHT AVVNQYRMRG LNPGTVNSCC IPTKLSTMSM LYFDDEYNIV KRDVPNMIVE ECGCA
  • Activity
    The ED50 was determined by its ability to inhibit the proliferation of murine MPC - 11 cells is ≤ 2 ng/mL, corresponding to a specific activity of ≥ 5 x 105 units/mg.
  • Keep at
    The lyophilized Activin B recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Activin B is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Activin B recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
  • Rec PROTEIN GI
    154813204
  • Accession nr
    NP_002184.2
  • Pureity
    Greater than 95% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
  • About
    This product is for research use only.
  • Protein s origin
    Human
  • Vial
    Lyophilized
  • NCBI ID
    3625
  • Gene name
    inhibin, beta B
  • Source
    Homo sapiens
  • Uniprot
    P09529
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    INHBB
  • Short name
    Activin B Recombinant Protein
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Alternative name
    Activin B Rec. Protein
  • Alternative technique
    rec
Gene info
  • Identity
  • Gene
  • Long gene name
    inhibin subunit beta B
  • Synonyms gene name
    • inhibin, beta B (activin AB beta polypeptide)
    • inhibin, beta B
  • Locus
  • Discovery year
    1986-01-01
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Inhibin subunits
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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