Rabbit anti Ubiquitin Specific Protease 4 (USP4)
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Catalog number
X2232P
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Price
Please ask
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Size
50 μg
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Category
Primary Antibodies
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Long description
Ubiquitin Specific Protease 4 is a hydrolase that deubiquitinates target proteins such as the receptor ADORA2A and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. This protein plays a role in the regulation of quality control in the ER. USP4 interacts with RB1 (both dephosphorylated and hypophosphorylated forms) and with ADORA2A (via cytoplasmic C-terminus); The interaction is direct. It also interacts with RB1, RBL1 and RBL2. It is overexpressed in small cell tumors and adenocarcinomas of the lung compared to expression of the wild-type in the lung (at protein level). USP4 is expressed in the hippocampal neurons.
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Antibody come from
internal domain of human
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Other description
Phosphate buffered saline containing 0.1% sodium azide. Immunoaffinity Purification
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Clone
Polyclonal
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Antigen antibody binding interaction
Rabbit anti Ubiquitin Specific Protease 4 (USP4) Antibody
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Antibody is raised in
Rabbit
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Antibody s reacts with
Human
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Antibody s reacts with these species
This antibody doesn't cross react with other species
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Antibody s specificity
No Data Available
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Application
Immunohistochemistry
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Antibody s suited for
Optimal concentration should be evaluated by serial dilutions.
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Storage
Long term: -70ºC; Short term: +4ºC
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Relevant references
no information yet
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Protein number
see ncbi
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Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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About
Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
USP4
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Short name
Rabbit anti Ubiquitin Specific Protease 4 (USP4)
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Technique
Rabbit, anti, antibody to
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Host
Rabbit, Rabbits
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Isotype
not specified
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Label
unlabeled
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Alternative name
production species: rabbit antibody to Ubiquitin Specific Protease 4 (ubiquitin specific peptidase 4 (proto-oncogene))
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Alternative technique
rabbit-anti, antibodies
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Alternative to gene target
ubiquitin specific peptidase 4 (proto-oncogene), UNP and Unph, USP4 and IDBG-34595 and ENSG00000114316 and 102724426,7375, metal ion binding, nuclei, Usp4 and IDBG-199676 and ENSMUSG00000032612 and 22258, USP4 and IDBG-646000 and ENSBTAG00000011899 and 508042
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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