Rabbit anti Paired Basic Amino Acid Cleaving System 4 (PACE4) (PCSK6)

• Catalog number
  X2227P
• Price
  Please ask
• Size
  50 μg

• Category
  Primary Antibodies
• Long description
  PACE4 is a Serine S8 type protease that cleaves precursor proteins at paired basic amino acid processing sites. Several PACE4 substrates have been identified, including transforming growth factor beta-related proteins, proalbumin and von Willebrand factor. At least eight alternatively spliced transcript variants encoding different isoforms have been reported. In mouse, PACE4 has been shown to increase tumor cell invasiveness, and thus enhance tumor progression.
• Antibody come from
  N-terminal region of human
• Other description
  Phosphate buffered saline containing 0.1% sodium azide. Immunoaffinity Purification
• Clone
  Polyclonal
• Antigen antibody binding interaction
  Rabbit anti Paired Basic Amino Acid Cleaving System 4 (PACE4) (PCSK6) Antibody
• Antibody is raised in
  Rabbit
• Antibody s reacts with
  Human
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Immunohistochemistry
• Antibody s suited for
  Antibody can be used for immunohistochemistry on formalin-fixed, paraffin-embedded tissues (10-15 µg/ml). Optimal concentration should be evaluated by serial dilutions.
• Storage
  Long term: -70ºC; Short term: +4ºC
• Relevant references
  no information yet
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Basic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer.
• About
  Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  Paired   Amino   Acid   Cleaving   PACE4   PCSK6  
• Gene symbol
  PCSK6, PCSK6-AS1
• Short name
  Rabbit anti Paired Amino Acid Cleaving System 4 (PACE4) (PCSK6)
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  production species: rabbit antibody to Paired Basic Amino Acid Cleaving System 4 (PACE4) (PCSK6)
• Alternative technique
  rabbit-anti, antibodies

Gene info

• Identity
  HGNC:8569
• Gene
  PCSK6
• Long gene name
  proprotein convertase subtilisin/kexin type 6
• Synonyms gene
  • PACE4
• Synonyms gene name
  • paired basic amino acid cleaving system 4
• Synonyms
  • SPC4
• Synonyms name
  • subtilisin-like protease
  • subtilisin-like proprotein convertase 4
  • subtilisin/kexin-like protease PACE4
• Locus
  15q26.3
• Discovery year
  1992-06-05
• Entrez gene record
  5046
• Pubmed identfication
  • 1741956
• RefSeq identity
  • NM_002570
• Classification
  • Proprotein convertase subtilisin/kexin family
• VEGA ID
  OTTHUMG00000172097
• Locus Specific Databases
  • LRG_888

Gene info

• Identity
  HGNC:51448
• Gene
  PCSK6-AS1
• Long gene name
  PCSK6 antisense RNA 1
• GenBank acession
  • BG505308
• Locus
  15q26.3
• Discovery year
  2014-11-28
• Pubmed identfication
  • 26908617
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000172093

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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