Rabbit anti Histone H2A.x
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Catalog number
X2753P
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Price
Please ask
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Size
100 μg
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Category
Primary Antibodies
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Long description
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
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Antibody come from
n/a
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Other description
Provided as solution in phosphate buffered saline with 0.08% sodium azide. Antigen Immunoaffiinity Purification
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Clone
Polyclonal
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Antigen antibody binding interaction
Rabbit anti Histone H2A.x Antibody
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Antibody is raised in
Rabbit
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Antibody s reacts with
Human
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Antibody s reacts with these species
This antibody doesn't cross react with other species
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Antibody s specificity
No Data Available
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Application
Western blot, Immunohistochemistry, EIA
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Antibody s suited for
Optimal concentration should be evaluated by serial dilutions.
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Storage
-20ºC
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Relevant references
no information yet
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Protein number
see ncbi
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Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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About
Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
H2AC20, H2AC7, H2AC18, H2AC8, H2AC17, H2AC11, H2AC19, H2AC15, H2AC4, H2AC13
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Short name
Rabbit anti Histone H2A x
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Technique
Rabbit, anti, antibody to
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Host
Rabbit, Rabbits
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Isotype
not specified
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Label
unlabeled
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Alternative name
production species: rabbit antibody to Histone H2A.x
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Alternative technique
rabbit-anti, antibodies
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Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 20
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Synonyms gene
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Synonyms gene name
- H2A histone family, member Q
- histone 2, H2ac
- histone cluster 2, H2ac
- histone cluster 2 H2A family member c
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 7
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Synonyms gene
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Synonyms gene name
- H2A histone family, member G
- histone 1, H2ad
- histone cluster 1, H2ad
- histone cluster 1 H2A family member d
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Synonyms
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GenBank acession
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Locus
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Discovery year
1997-08-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 18
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Synonyms gene
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Synonyms gene name
- H2A histone family, member O
- histone 2, H2aa
- histone 2, H2aa3
- histone cluster 2, H2aa3
- histone cluster 2 H2A family member a3
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 8
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Synonyms gene
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Synonyms gene name
- H2A histone family, member A
- histone 1, H2ae
- histone cluster 1, H2ae
- histone cluster 1 H2A family member e
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Synonyms
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GenBank acession
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Locus
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Discovery year
1997-08-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 17
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Synonyms gene
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Synonyms gene name
- H2A histone family, member N
- histone 1, H2am
- histone cluster 1, H2am
- histone cluster 1 H2A family member m
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 11
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Synonyms gene
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Synonyms gene name
- H2A histone family, member P
- histone 1, H2ag
- histone cluster 1, H2ag
- histone cluster 1 H2A family member g
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-10-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 19
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Synonyms gene
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Synonyms gene name
- histone 2, H2aa4
- histone cluster 2, H2aa4
- histone cluster 2 H2A family member a4
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Synonyms
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GenBank acession
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Locus
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Discovery year
2006-06-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 15
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Synonyms gene
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Synonyms gene name
- H2A histone family, member D
- histone 1, H2ak
- histone cluster 1, H2ak
- histone cluster 1 H2A family member k
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 4
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Synonyms gene
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Synonyms gene name
- H2A histone family, member M
- histone 1, H2ab
- histone cluster 1, H2ab
- histone cluster 1 H2A family member b
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2A clustered histone 13
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Synonyms gene
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Synonyms gene name
- H2A histone family, member C
- histone 1, H2ai
- histone cluster 1, H2ai
- histone cluster 1 H2A family member i
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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