Rabbit anti CXCR6 (NT)

  • Catalog number
    X1143P
  • Price
    Please ask
  • Size
    100 μg
  • Category
    Primary Antibodies
  • Long description
    Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as an HIV and SIV coreceptor1-4. Bonzo/STRL33 is used by SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.
  • Antibody come from
    Antibody raised against a synthetic peptide corresponding to amino acids 11 to 25 of the human Bonzo protein. Peptide sequence differs from those of African green monkey and pig-tailed macaque by one or two amino acids, respectively.
  • Other description
    Provided in phosphate buffered saline solution containing 0.02% sodium azide as a preservative. Antigen Immunoaffiinity Purification
  • Clone
    Polyclonal
  • Antigen antibody binding interaction
    Rabbit anti CXCR6 (NT) Antibody
  • Antibody is raised in
    Rabbit
  • Antibody s reacts with
    Human
  • Antibody s reacts with these species
    This antibody doesn't cross react with other species
  • Antibody s specificity
    No Data Available
  • Application
    Western Blot
  • Antibody s suited for
    Detects Bonzo protein by Western blot at 0.5 to 1 µg/ml. Detects an approximately 45 kDa band in human spleen tissue lysate. Optimal concentration should be evaluated by serial dilutions.
  • Storage
    -20ºC
  • Relevant references
    1. Deng, H.K., et al. 'Expression cloning of new receptors used by simian and human immunodeficiency viruses.' Nature 1997, 388, 296-300 _x000B__x000B_2. Liao, F., et al. 'STRL33, A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1.' J. Exp. Med. 1997, 185, 2015-2023 _x000B__x000B_3. Alkhatib, G., et al. 'A new SIV co-receptor, STRL33.' Nature 1997, 388, 238 _x000B__x000B_4. Loetscher, M., et al. 'TYMSTR, a putative chemokine receptor selectively expressed in activated T cells, exhibits HIV-1 coreceptor function.' Curr. Biol. 1997, 7, 652-660_x000B_
  • Protein number
    see ncbi
  • Warnings
    This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • About
    Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
  • Latin name
    Oryctolagus cuniculus
  • Gene target
    CXCR6  
  • Gene symbol
    CXCR6
  • Short name
    Rabbit anti CXCR6 (NT)
  • Technique
    Rabbit, anti, antibody to
  • Host
    Rabbit, Rabbits
  • Isotype
    not specified
  • Label
    unlabeled
  • Alternative name
    production species: rabbit antibody to chemokine (C-X-C motif) receptor 6 (NT)
  • Alternative technique
    rabbit-anti, antibodies
  • Alternative to gene target
    chemokine (C-X-C motif) receptor 6, BONZO and CD186 and STRL33 and TYMSTR, CXCR6 and IDBG-29993 and ENSG00000172215 and 10663, C-X-C chemokine receptor activity, Plasma membranes, Cxcr6 and IDBG-206490 and ENSMUSG00000048521 and 80901, CXCR6 and IDBG-646261 and ENSBTAG00000015708 and 506807
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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