Mouse anti Receptor-Like Tyrosine Kinase

• Catalog number
  X2072M
• Price
  Please ask
• Size
  200 μg

• Category
  Primary Antibodies
• Long description
  RYK (Receptor like Tyrosine kinase 1) is in the Tyrosine family of receptor kinases. It is found in the plasma membrane of heart, prostate and kidney cells. RYK contains 604 amino acids and it contains one WIF domain. It functions as a potential growth factor receptor protein tyrosine kinase. RYK are divergent from those of other classic receptor tyrosine kinases. It is an orphan receptor that contains a catalytically inactive tyrosine kinase related domain. RYK is expressed in nestin positive progenitor cells and neurons, and in a certain population of oligodendrocytes, O2A progenitor cells, and type 2 astrocytes in developing CNS.
• Antibody come from
  Synthetic protein made to the 3rd cytoplasmic domain of human Muscarinic Acetylcholine Receptor M3 linked to KLH
• Other description
  Phosphate buffered saline containing 0.1% sodium azide. Protein A/G Chromatography
• Clone
  F35 P7 D7 F5
• Antigen antibody binding interaction
  Mouse anti Receptor-Like Tyrosine Kinase Antibody
• Antibody is raised in
  Mouse
• Antibody s reacts with
  Human, Mouse, Rat
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Western Blot
• Antibody s suited for
  Antibody can be used for immunohistochemistry (5-10 µg/ml, formalin fixed-paraffin embedded tissue). Optimal concentration should be evaluated by serial dilutions.
• Storage
  -80ºC
• Relevant references
  no information yet
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Receptor-Like   Tyrosine   Kinase  
• Gene symbol
  RYKP1, RYK, ROR2
• Short name
  Mouse anti Receptor-Like Tyrosine Kinase
• Technique
  Mouse, anti, antibody to, mouses
• Host
  mouse
• Isotype
  IgG1
• Label
  unlabeled
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to Receptor-Like Tyrosine phosphorylation catalyst
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:10482
• Gene
  RYKP1
• Long gene name
  RYK pseudogene 1
• Synonyms gene
  • RYKL1
  • JTK5B
  • RYKP
• Synonyms gene name
  • RYK receptor-like tyrosine kinase-like 1
  • JTK5B protein tyrosine kinase
  • RYK receptor-like tyrosine kinase pseudogene
  • RYK receptor-like tyrosine kinase pseudogene 1
  • receptor-like tyrosine kinase pseudogene 1
• Synonyms
  • JTK5
• GenBank acession
  • AC087742
• Locus
  17p13.2
• Discovery year
  1993-09-28
• Entrez gene record
  6260
• Pubmed identfication
  • 8386829
  • 10066802
• RefSeq identity
  • NG_005810
• VEGA ID
  OTTHUMG00000177729

Gene info

• Identity
  HGNC:10481
• Gene
  RYK
• Long gene name
  receptor like tyrosine kinase
• Synonyms gene
  • JTK5A
• Synonyms gene name
  • JTK5A protein tyrosine kinase
  • RYK receptor-like tyrosine kinase
• Synonyms
  • D3S3195
  • RYK1
  • JTK5
• GenBank acession
  • S59184
• Locus
  3q22.2
• Discovery year
  1993-09-28
• Entrez gene record
  6259
• Pubmed identfication
  • 8386829
• RefSeq identity
  • NM_001005861
• Classification
  • Receptor tyrosine kinases
• VEGA ID
  OTTHUMG00000159750

Gene info

• Identity
  HGNC:10257
• Gene
  ROR2
• Long gene name
  receptor tyrosine kinase like orphan receptor 2
• Synonyms gene
  • NTRKR2
  • BDB
  • BDB1
• Synonyms gene name
  • receptor tyrosine kinase-like orphan receptor 2
• GenBank acession
  • M97639
• Locus
  9q22.31
• Discovery year
  2000-02-29
• Entrez gene record
  4920
• Pubmed identfication
  • 1334494
  • 10700182
• Classification
  • Receptor tyrosine kinases
  • I-set domain containing
• VEGA ID
  OTTHUMG00000020211
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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