Mouse anti Interleukin 10 (IL-10)

  • Catalog number
    X2388M
  • Price
    Please ask
  • Size
    500 μg
  • Category
    Primary Antibodies
  • Long description
    Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.Defects in IL10 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease.
  • Antibody come from
    Synthetic peptide derived from the human SUMO-1 protein.
  • Other description
    Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
  • Clone
    945A5D11
  • Antigen antibody binding interaction
    Mouse anti Interleukin 10 (IL-10) Antibody
  • Antibody is raised in
    Mouse
  • Antibody s reacts with
    Human
  • Antibody s reacts with these species
    This antibody doesn't cross react with other species
  • Antibody s specificity
    No Data Available
  • Application
    ELISA
  • Antibody s suited for
    Antibody can be used for Western blotting (1-5 µg/ml). Optimal concentration should be evaluated by serial dilutions.
  • Storage
    -80ºC
  • Relevant references
    1. Saitoh, H., et al. 'SUMO-1: wrestling with a new ubiquitin-related modifier.' Trends Biochem Sci 1997; 22(10):374-376_x000B__x000B_2. Muller, S., et al. 'Conjugation with the ubiquitin-related modifier SUMO-1 regulated the partitioning of PML within the nucleus.' EMBO J 1998; 17(1):61-70_x000B__x000B_3. Navascues J., et al. 'SUMO-1 transiently localizes to Cajal bodies in mammalian neurons.' J Struct Biol 2008; 163(2):137-146.
  • Protein number
    see ncbi
  • Warnings
    This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Gene target
  • Gene symbol
    IL10, SNORD115-10, PIRC49, SNORD116-10, IL36G, IL25, IGKV2OR2-10
  • Short name
    Mouse anti Interleukin 10 (IL-10)
  • Technique
    Mouse, anti, antibody to, mouses
  • Host
    mouse
  • Isotype
    IgG1
  • Label
    unlabeled
  • Species
    Mouse, Mouses
  • Alternative name
    Mouse antibody to Interleukin 10 (Interleukin-10)
  • Alternative technique
    murine, antibodies
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    piwi-interacting RNA cluster 49
  • Locus
    10
  • Discovery year
    2009-11-05
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Piwi-interacting RNA clusters
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin kappa variable 2/OR2-10 (pseudogene)
  • Synonyms gene name
    • immunoglobulin kappa variable 2/OR2-10
    • immunoglobulin kappa variable 2/OR2-10 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-18
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin kappa (IGK) orphons
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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