Mouse anti IL-6 Receptor

  • Catalog number
    X1948M
  • Price
    Please ask
  • Size
    100 μg
  • Category
    Primary Antibodies
  • Long description
    IL-6R (B-R6) MAb MS X HU; Unconjugated Monoclonal antibody specific to Human IL-6R. This antibody is validated for use in Flow Cytometry, Immunoassay (ELISA). Anti-IL-6R recognizes the expressed product of the IL6R gene.
  • Antibody come from
    Recombinant human p70-S6K protein
  • Other description
    Provided as solution in phosphate buffered saline, pH 7.2, with 1% BSA and 0.1% sodium azide. Purified by ion exchange chromatography.
  • Clone
    B-R6
  • Antigen antibody binding interaction
    Mouse anti IL-6 Receptor Antibody
  • Antibody is raised in
    Mouse
  • Antibody s reacts with
    Human
  • Antibody s reacts with these species
    This antibody doesn't cross react with other species
  • Antibody s specificity
    No Data Available
  • Application
    ELISA, Neutralization, Flow Cytometry
  • Antibody s suited for
    Optimal concentration should be evaluated by serial dilutions. For Western blotting, the recommended concentration is 1 µg/mL
  • Storage
    -20ºC
  • Relevant references
    1. Tu, V.C., et al. (2002) Signals of oxidant-induced cardiomyocyte hypertrophy: key activation of p70 S6 kinase-1 and phosphoinositide 3-kinase. J. Pharmacol. Exp. Ther. _x000B_300(3):1101-1110._x000B_2. Zhang, Y., et al. (2001) Induction of EGFR-dependent and EGFR-independent signaling pathways by ultraviolet A irradiation. DNA Cell. Biol. 20(12):769-779._x000B_3. Gonzalez-Garcia, A., et al. (2002) A new role for the p85-phosphatidylinositol 3-kinase regulatory subunit linking FRAP to p70 S6 kinase activation. J. Biol. Chem. _x000B_277(2):1500-1508._x000B_
  • Protein number
    see ncbi
  • Warnings
    This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Gene target
    IL-6   Receptor  
  • Gene symbol
    IL6, IL6-AS1, IL36G, IL25, IL22, IL18, IL37, IL6R, IL17C, IL17A
  • Short name
    Mouse anti IL-6 Receptor
  • Technique
    Mouse, anti, antibody to, mouses
  • Host
    mouse
  • Isotype
    IgG1
  • Label
    unlabeled
  • Species
    Mouse, Mouses
  • Alternative name
    Mouse antibody to Interleukin-6 Receptor
  • Alternative technique
    murine, antibodies
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    IL6 antisense RNA 1
  • Locus
  • Discovery year
    2019-08-14
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Antisense RNAs
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
Filters
Contact
Chat with gentaur.com employee