Mouse anti Cytochrome P450 4F11
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Catalog numberX2052M
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PricePlease ask
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Size200 μg
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CategoryPrimary Antibodies
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Long descriptionThe cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP4F11 is an isoform of the cytochrome P450 4F protein and is expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. CYP4F11 contains 524 amino acid residues that share 80.0, 82.3 and 79.2% identity to CYP4F2, CYP4F3, and CYP4F8 amino acid sequences, respectively. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.
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Antibody come fromHybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the human NSE protein and mouse myeloma Ag8563 cells. Sequence common in human, mouse and chicken.
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Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
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CloneF21 P6 F5
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Antigen antibody binding interactionMouse anti Cytochrome P450 4F11 Antibody
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Antibody is raised inMouse
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Antibody s reacts withHuman
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Antibody s reacts with these speciesThis antibody doesn't cross react with other species
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Antibody s specificityNo Data Available
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ApplicationELISA, Western Blot, Immunohistochemistry
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Antibody s suited forAntibody can be used for Western blotting (1-2 µg/ml) and immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections (1-5µg/ml). Optimal concentration should be evaluated by serial dilutions.
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Storage-20ºC
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Relevant references1. Kang, J.L., et al. (1996). Immunoreactive neuron-specific enolase (NSE) is expressed in testicular carcinoma-in-situ. J. Pathol. 178(2):161-165._x000B__x000B_2. Koch, M., et al. (2007). Plasma S100beta and NSE levels and progression in multiple sclerosis. J. Neurol. Sci. 252(2):154-158._x000B__x000B_3. Oertel, M., et al. (2006). S-100B and NSE: markers of initial impact of subarachnoid haemorrhage and their relation to vasospasm and outcome. J. Clin. Neurosci. 13(8):834-840.
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Protein numbersee ncbi
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WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolCYP3A7, CYP24A1, CYP1A1, CYP51A1, CYP2D6
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Short nameMouse anti Cytochrome P450 4F11
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TechniqueMouse, anti, antibody to, mouses
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Hostmouse
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IsotypeIgG1
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Labelunlabeled
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SpeciesMouse, Mouses
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Alternative nameMouse antibody to Cytochrome P450 4F11
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Alternative techniquemurine, antibodies
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Gene info
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Identity
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Gene
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Long gene namecytochrome P450 family 3 subfamily A member 7
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Synonyms gene name
- cytochrome P450, subfamily IIIA, polypeptide 7
- cytochrome P450, family 3, subfamily A, polypeptide 7
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-09-14
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Entrez gene record
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Pubmed identfication
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Classification
- Cytochrome P450 family 3
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecytochrome P450 family 24 subfamily A member 1
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Synonyms gene
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Synonyms gene name
- cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)
- cytochrome P450, family 24, subfamily A, polypeptide 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-09-09
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Entrez gene record
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Classification
- Cytochrome P450 family 24
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecytochrome P450 family 1 subfamily A member 1
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Synonyms gene
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Synonyms gene name
- cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1
- cytochrome P450, family 1, subfamily A, polypeptide 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Cytochrome P450 family 1
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecytochrome P450 family 51 subfamily A member 1
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Synonyms gene
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Synonyms gene name
- cytochrome P450, 51 (lanosterol 14-alpha-demethylase)
- cytochrome P450, family 51, subfamily A, polypeptide 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-10-26
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Entrez gene record
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Pubmed identfication
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Classification
- Cytochrome P450 family 51
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecytochrome P450 family 2 subfamily D member 6
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Synonyms gene
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Synonyms gene name
- cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6
- cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2
- cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2
- cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2
- cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2
- cytochrome P450, family 2, subfamily D, polypeptide 6
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-04-07
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Entrez gene record
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Pubmed identfication
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Classification
- Cytochrome P450 family 2
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data