Mouse anti Cytochrome P450 4F11

  • Catalog number
    X2052M
  • Price
    Please ask
  • Size
    200 μg
  • Category
    Primary Antibodies
  • Long description
    The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP4F11 is an isoform of the cytochrome P450 4F protein and is expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. CYP4F11 contains 524 amino acid residues that share 80.0, 82.3 and 79.2% identity to CYP4F2, CYP4F3, and CYP4F8 amino acid sequences, respectively. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.
  • Antibody come from
    Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the human NSE protein and mouse myeloma Ag8563 cells. Sequence common in human, mouse and chicken.
  • Other description
    Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
  • Clone
    F21 P6 F5
  • Antigen antibody binding interaction
    Mouse anti Cytochrome P450 4F11 Antibody
  • Antibody is raised in
    Mouse
  • Antibody s reacts with
    Human
  • Antibody s reacts with these species
    This antibody doesn't cross react with other species
  • Antibody s specificity
    No Data Available
  • Application
    ELISA, Western Blot, Immunohistochemistry
  • Antibody s suited for
    Antibody can be used for Western blotting (1-2 µg/ml) and immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections (1-5µg/ml). Optimal concentration should be evaluated by serial dilutions.
  • Storage
    -20ºC
  • Relevant references
    1. Kang, J.L., et al. (1996). Immunoreactive neuron-specific enolase (NSE) is expressed in testicular carcinoma-in-situ. J. Pathol. 178(2):161-165._x000B__x000B_2. Koch, M., et al. (2007). Plasma S100beta and NSE levels and progression in multiple sclerosis. J. Neurol. Sci. 252(2):154-158._x000B__x000B_3. Oertel, M., et al. (2006). S-100B and NSE: markers of initial impact of subarachnoid haemorrhage and their relation to vasospasm and outcome. J. Clin. Neurosci. 13(8):834-840.
  • Protein number
    see ncbi
  • Warnings
    This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Gene target
    Cytochrome   P450   4F11  
  • Gene symbol
    CYP3A7, CYP24A1, CYP1A1, CYP51A1, CYP2D6
  • Short name
    Mouse anti Cytochrome P450 4F11
  • Technique
    Mouse, anti, antibody to, mouses
  • Host
    mouse
  • Isotype
    IgG1
  • Label
    unlabeled
  • Species
    Mouse, Mouses
  • Alternative name
    Mouse antibody to Cytochrome P450 4F11
  • Alternative technique
    murine, antibodies
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    cytochrome P450 family 24 subfamily A member 1
  • Synonyms gene
  • Synonyms gene name
    • cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)
    • cytochrome P450, family 24, subfamily A, polypeptide 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1992-09-09
  • Entrez gene record
  • Classification
    • Cytochrome P450 family 24
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    cytochrome P450 family 51 subfamily A member 1
  • Synonyms gene
  • Synonyms gene name
    • cytochrome P450, 51 (lanosterol 14-alpha-demethylase)
    • cytochrome P450, family 51, subfamily A, polypeptide 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1996-10-26
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Cytochrome P450 family 51
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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