Mouse anti CXCR2

  • Catalog number
    X1894M
  • Price
    Please ask
  • Size
    100 μg
  • Category
    Primary Antibodies
  • Long description
    CXCR1 and CXCR2, previously known as IL-8RA, or type I IL-8 receptor, and IL-8RB, or type II IL-8 receptor, respectively, have been shown to share approximately 77% amino acid sequence identity. IL-8 binds to both receptors with high affinity and induces rapid elevation of cytosolic Ca2+ levels. While IL-8 and Granulocyte Chemotactic Protein 2 (GCP2) have been shown to exert their biological activity by binding to both receptors, GRO , GRO , GRO , NAP-2 and ENA-78 bind only to CXCR2. CXCR1 and CXCR2 are expressed on neutrophils and mast cells, but not on B or T lymphocytes. In cells transfected with either CXCR1 or CXCR2, clone 19 showed no cross-reactivity with CXCR1.
  • Antibody come from
    Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with human recombinant IL-2 protein and NSO mouse myeloma cells.
  • Other description
    Provided as solution in phosphate buffered saline with 0.05% sodium azide. Protein A/G Chromatography
  • Clone
    19
  • Antigen antibody binding interaction
    Mouse anti CXCR2 Antibody
  • Antibody is raised in
    Mouse
  • Antibody s reacts with
    Human
  • Antibody s reacts with these species
    This antibody doesn't cross react with other species
  • Antibody s specificity
    No Data Available
  • Application
    ELISA, Neurtralization, Western Blot, Immunohistochemistry, Immunocytochemistry,Flow Cytometry
  • Antibody s suited for
    Antibody can be used for immunohistochemistry and ELISA as the detection antibody. Optimal concentration should be evaluated by serial dilutions.
  • Storage
    -20ºC
  • Relevant references
    1. Denny, M.F., et al., 'Differential T-cell antigen receptor signaling mediated by the Src family kinases Lck and Fyn.' (2000) Mol. Cell. Biol. 20(4):1426-1435.
  • Protein number
    see ncbi
  • Warnings
    This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Gene target
    CXCR2  
  • Gene symbol
    CXCR2
  • Short name
    Mouse anti CXCR2
  • Technique
    Mouse, anti, antibody to, mouses
  • Host
    mouse
  • Isotype
    IgG1
  • Label
    unlabeled
  • Species
    Mouse, Mouses
  • Alternative name
    Mouse antibody to chemokine (C-X-C motif) receptor 2
  • Alternative technique
    murine, antibodies
  • Alternative to gene target
    chemokine (C-X-C motif) receptor 2, CD182 and CDw128b and CMKAR2 and IL8R2 and IL8RA and IL8RB, CXCR2 and IDBG-80804 and ENSG00000180871 and 3579, interleukin-8 binding, Cell surfaces, Cxcr2 and IDBG-166395 and ENSMUSG00000026180 and 12765
Gene info
  • Identity
  • Gene
  • Long gene name
    C-X-C motif chemokine receptor 2
  • Synonyms gene
  • Synonyms gene name
    • interleukin 8 receptor, beta
    • chemokine (C-X-C motif) receptor 2
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1991-08-19
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Interleukin receptors
    • C-X-C motif chemokine receptors
    • CD molecules
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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