CEACAM 1,5,6,8 (Carcinoembryonic Antigen Related Cell Adhesion Molecule)

• Catalog number
  GEN605819
• Price
  Please ask
• Size
  100ug

• Also known as
  CEACAM 1,5,6,8
• Other names
  carcinoembryonic antigen-related cell adhesion molecule 5 preproprotein; Carcinoembryonic antigen-related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 5; meconium antigen 100; carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  CEACAM5; CEACAM5; CEA; CD66e; CEA; CEA
• Gene name synonims
  CEACAM5; CEACAM5; CEA; CD66e; CEA; CEA
• Other gene names
  CEACAM5; CEACAM5; CEA; CD66e; CEA; CEA
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2b
• Clone
  5E503
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Broadly reactive antibody which reacts with most of the CEACAM molecules characterized to date (except CEACAM3, CEACAM4 and CEACAM7) (4). Can be used to detect CEACAM1 (BGP/CD66a), CEACAM5 (CEA/CD66e), CEACAM6 (NCA/CD66c) and CEACAM8 (CGM6/CD66b) on transiently transfected BOSC23 cells by flow cytometry. Included and characterized in the studies from the VIth Leucocyte Typing Workshop (4).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography from cell culture supernatants and is routinely tested by flow cytometry on BOSC23 cells transiently transfected with a CEACAM5 expression vector.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze the antibody should be stored at -20 degrees Celsius.. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
• Description
  cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the CEACAM 1 5 6 8 (Carcinoembryonic Antigen Adhesion Molecule). Antigens are peptides or recombinant or native dependent on the production method. For cells, cell lines and tissues in culture till half confluency. Whole adhesion and interacting molecules are  present in lysates used as reference for ELISA quantification of these molecules and their subunits.

• Gene target
  CEACAM   Carcinoembryonic   Related   Adhesion   Molecule  
• Short name
  CEACAM 1 5 6 8 (Carcinoembryonic Antigen Adhesion Molecule)
• Technique
  antigen, antigenes
• Alternative name
  Anti-CEACAM 1,5,6,8 (Carcinoembryonic Antigen Related Cell Adhesion Molecule)
• Alternative technique
  antigenes
• Tissue
  cell

MeSH Data

• Name
  Embryo Research
• Concept
  Scope note: Experimentation on, or using the organs or tissues from, a human or other mammalian conceptus during the prenatal stage of development that is characterized by rapid morphological changes and the differentiation of basic structures. In humans, this includes the period from the time of fertilization to the end of the eighth week after fertilization.
• Tree numbers
  • E05.313
• Qualifiers
  economics, ethics, history, legislation & jurisprudence

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