Sheep anti TGF beta II receptor (27-85)

  • Catalog number
    L110P
  • Price
    Please ask
  • Size
    50 μg
  • Category
    Primary Antibodies
  • Long description
    The immunogen used was a recombinant protein containing chick transforming growth factor type II receptor region a.a.27-85. Epithelial-mesenchymal transformation is a critical event in the development of many organ systems including heart. Transforming Growth Factor (TGF ) is one of a number of factors that mediates this transformation. Antibodies directed against TGF Type II receptor block both the endicardial cell activation and subsequent migration that constitute transformation in the chick atrioventricular (AV) cushion.
  • Antibody come from
    A recombinant protein containing chick transforming growth factor type II receptor a.a.27-85
  • Other description
    Provided as solution in phosphate buffered saline with 0.08% sodium azide. Ammonium Sulfate Precipitation
  • Clone
    Polyclonal
  • Antigen antibody binding interaction
    Sheep anti TGF beta II receptor (27-85) Antibody
  • Antibody is raised in
    Sheep
  • Antibody s reacts with
    Chicken
  • Antibody s reacts with these species
    This antibody doesn't cross react with other species
  • Antibody s specificity
    No Data Available
  • Application
    Immunohistochemistry
  • Antibody s suited for
    Applications: Western Blot (1:100), Immunohistology, Empirical
  • Storage
    -20ºC
  • Relevant references
    C. Brown, et. al. (1999) Dev. Dynamics, 1-7
  • Protein number
    see ncbi
  • Warnings
    This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Gene target
    TGF   beta   receptor   27-85  
  • Gene symbol
    SNORD116-27, SNORD115-27, IGKV1D-27, RNVU1-27, IGHV7-27, ERVK-27, ERVW-27, SNORD114-27, IGLV3-27, KMT5B
  • Short name
    anti TGF beta II receptor (27-85)
  • Technique
    anti, antibody to
  • Host
    Sheep
  • Isotype
    not specified
  • Label
    unlabeled
  • Species
    Sheep, The sheep (Ovis aries) ELISAs are detecting sheep proteins and antigens. Some epitopes will also recognize goat proteins. Sheep and goats are also used to produce polyclonals. An adult female sheep is referred to as a ewe a male as a ram, a castrated male as a wether, and a younger sheep as a lamb. Sheeps
  • Alternative name
    ovine antibody to TGF b II receptor (27-85)
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin kappa variable 1D-27 (pseudogene)
  • Synonyms gene name
    • immunoglobulin kappa variable 1D-27
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-18
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin kappa locus at 2p11.2
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    RNA, variant U1 small nuclear 27
  • Locus
  • Discovery year
    2019-07-26
  • Classification
    • Variant U1 small nuclear RNAs
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable 7-27 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable 7-27
    • immunoglobulin heavy variable 7-27 pseudogene
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-04
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    endogenous retrovirus group K member 27
  • Synonyms gene name
    • endogenous retrovirus group K, member 27
  • GenBank acession
  • Locus
  • Discovery year
    2014-01-03
  • Pubmed identfication
Gene info
  • Identity
  • Gene
  • Long gene name
    endogenous retrovirus group W member 27
  • Synonyms gene name
    • endogenous retrovirus group W, member 27
  • GenBank acession
  • Locus
  • Discovery year
    2013-10-21
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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