Sheep anti PTEN
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Catalog numberD100P
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PricePlease ask
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Size250 μg
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CategoryPrimary Antibodies
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Long descriptionLoss of chromosome 10q is a frequently observed genetic defect in prostate cancer. Recently, the PTEN/MMAC1 tumor suppressor gene was identified and mapped to chromosome 10q23.3. PTEN is often found mutated in various cancers. The high frequency (60%) of PTEN mutations and deletions found in prostate cancer samples indicates a significant role of this tumor suppressor gene in the pathogenesis of prostate cancer. PTEN mRNA expression was clearly observed in all cell lines and xenografts without large homozygous deletions, showing that PTEN downregulation is not an important mechanism of PTEN inactivation. The immunogen used was a GST-pTEN fusion protein a.a. seq. 188-403.
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Antibody come fromA GST-pTEN fusion protein a.a. seq. 188-403
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Other descriptionProvided as solution in phosphate buffered saline with 0.08% sodium azide. Ammonium Sulfate Precipitation
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ClonePolyclonal
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Antigen antibody binding interactionSheep anti PTEN Antibody
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Antibody is raised inSheep
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Antibody s reacts withHuman
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Antibody s reacts with these speciesThis antibody doesn't cross react with other species
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Antibody s specificityNo Data Available
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ApplicationWestern Blot, Immunoprecipitation,
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Antibody s suited forApplications: Western Blot
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Storage-20ºC
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Relevant referencesno information yet
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Protein numbersee ncbi
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WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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Gene target
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Gene symbolPTEN, PTENP1
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Short nameanti PTEN
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Techniqueanti, antibody to
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HostSheep
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Isotypenot specified
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Labelunlabeled
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SpeciesSheep, The sheep (Ovis aries) ELISAs are detecting sheep proteins and antigens. Some epitopes will also recognize goat proteins. Sheep and goats are also used to produce polyclonals. An adult female sheep is referred to as a ewe a male as a ram, a castrated male as a wether, and a younger sheep as a lamb. Sheeps
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Alternative nameovine antibody to phosphatase and tensin homolog
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Alternative techniqueantibodies
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Alternative to gene targetphosphatase and tensin homolog, 10q23del and BZS and CWS1 and DEC and GLM2 and MHAM and MMAC1 and PTEN1 and TEP1, PTEN and IDBG-81409 and ENSG00000171862 and 5728, phosphatidylinositol-3, nuclei, Pten and IDBG-158878 and ENSMUSG00000013663 and 19211, PTEN and IDBG-637256 and ENSBTAG00000009498 and 540786
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Gene info
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Identity
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Gene
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Long gene namephosphatase and tensin homolog
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-04-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PTEN protein phosphatases
- C2 tensin-type domain containing
- Phosphoinositide phosphatases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namephosphatase and tensin homolog pseudogene 1
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Synonyms gene name
- phosphatase and tensin homolog pseudogene 1 (functional)
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-09-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
