Rat Anti-Mouse HGF Activator Inhibitor Type 2 (HAI-2)

• Catalog number
  GEN690526
• Price
  Please ask
• Size
  100ug

• Also known as
  HGF Activator Inhibitor Type 2 (HAI-2)
• Other names
  kunitz-type protease inhibitor 2 isoform b; Kunitz-type protease inhibitor 2; kunitz-type protease inhibitor 2; hepatocyte growth factor activator inhibitor type 2; serine protease inhibitor, Kunitz type 2; Hepatocyte growth factor activator inhibitor type 2
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  HAI-2
• Gene name synonims
  N/A
• Other gene names
  Spint2; Spint2; HAI-2; C76321; AL024025; Hai2; HAI-2
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2
• Clone
  (#7F52)
• Host organism
  Rat (Rattus norvegicus)
• Species reactivity
  Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  This antibody detects mouse HAI-2, but not HAI-1 in Western blotting.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Protein A/G affinity chromatography
• Form Appearance
  The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS). Lyophilized samples are stable for 2 years from date of receipt when stored at
• Concentration
  N/A
• Storage and shipping
  Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < Store the antibody at -20 degrees Celsius. for at least for six months without detectable loss of activity.
• Tested applications
  Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus, Rattus norvegicus
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

• Gene target
  HGF   Activator   Inhibitor   HAI-2  
• Gene symbol
  SPINT2, SPINT1, SOS1, HGF, IL6, ST14, MIR7-2, MIR329-2, MIR512-2, MIR521-2
• Short name
  Anti-Mouse HGF Activator Inhibitor 2 (HAI-2)
• Technique
  anti-, Mouse, anti, antibody to, antibodies, mouses
• Host
  Rat
• Species
  Mouse, Mouses, Rats
• Alternative name
  Anti-Rat Anti-Mouse HGF Activator Inhibitor Type 2 (HAI-2)
• Alternative technique
  murine, antibodies
• Alternative to gene target
  hepatocyte growth factor (hepapoietin A; scatter factor), DFNB39 and F-TCF and HGFB and HPTA and SF, HGF and IDBG-24150 and ENSG00000019991 and 3082, protein heterodimerization activity, Extracellular, Hgf and IDBG-136449 and ENSMUSG00000028864 and 15234, HGF and IDBG-631194 and ENSBTAG00000017664 and 282879

Gene info

• Identity
  HGNC:11247
• Gene
  SPINT2
• Long gene name
  serine peptidase inhibitor, Kunitz type 2
• Synonyms gene name
  • serine protease inhibitor, Kunitz type, 2
• Synonyms
  • Kop
  • HAI-2
• Synonyms name
  • placental bikunin
• GenBank acession
  • U78095
• Locus
  19q13.2
• Discovery year
  1999-07-23
• Entrez gene record
  10653
• Pubmed identfication
  • 9115294
  • 9346890
• VEGA ID
  OTTHUMG00000181891

Gene info

• Identity
  HGNC:11246
• Gene
  SPINT1
• Long gene name
  serine peptidase inhibitor, Kunitz type 1
• Synonyms gene name
  • serine protease inhibitor, Kunitz type 1
• Synonyms
  • HAI
  • MANSC2
• Locus
  15q15.1
• Discovery year
  1988-07-18
• Entrez gene record
  6692
• RefSeq identity
  • NM_003710
• VEGA ID
  OTTHUMG00000130068

Gene info

• Identity
  HGNC:11187
• Gene
  SOS1
• Long gene name
  SOS Ras/Rac guanine nucleotide exchange factor 1
• Synonyms gene
  • GINGF
• Synonyms gene name
  • gingival fibromatosis, hereditary, 1
  • son of sevenless homolog 1 (Drosophila)
• Synonyms
  • HGF
  • GF1
• GenBank acession
  • L13857
• Locus
  2p22.1
• Discovery year
  1993-10-27
• Entrez gene record
  6654
• Pubmed identfication
  • 8276400
  • 10995566
• RefSeq identity
  • NM_005633
• Classification
  • Dbl family Rho GEFs
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000102109
• Locus Specific Databases
  • LRG_754

Gene info

• Identity
  HGNC:4893
• Gene
  HGF
• Long gene name
  hepatocyte growth factor
• Synonyms gene
  • DFNB39
• Synonyms gene name
  • deafness, autosomal recessive 39
  • hepatocyte growth factor (hepapoietin A; scatter factor)
• Synonyms
  • SF
  • F-TCF
  • HGFB
  • HPTA
• Synonyms name
  • hepatopoietin A
  • fibroblast-derived tumor cytotoxic factor
  • scatter factor
  • lung fibroblast-derived mitogen
• Locus
  7q21.11
• Discovery year
  1991-06-07
• Entrez gene record
  3082
• Pubmed identfication
  • 1837206
  • 19576567
• RefSeq identity
  • NM_000601
• VEGA ID
  OTTHUMG00000023804

Gene info

• Identity
  HGNC:6018
• Gene
  IL6
• Long gene name
  interleukin 6
• Synonyms gene
  • IFNB2
• Synonyms gene name
  • interleukin 6 (interferon, beta 2)
• Synonyms
  • IL-6
  • BSF2
  • HGF
  • HSF
• Synonyms name
  • interferon, beta 2
• GenBank acession
  • M18403
• Locus
  7p15.3
• Discovery year
  1986-01-01
• Entrez gene record
  3569
• Pubmed identfication
  • 3294161
• RefSeq identity
  • NM_000600
• Classification
  • Interleukins
  • Interferons
  • Interleukin 6 type cytokine family
• VEGA ID
  OTTHUMG00000023178

Gene info

• Identity
  HGNC:11344
• Gene
  ST14
• Long gene name
  ST14 transmembrane serine protease matriptase
• Synonyms gene
  • PRSS14
• Synonyms gene name
  • suppression of tumorigenicity 14 (colon carcinoma)
  • suppression of tumorigenicity 14
• Synonyms
  • SNC19
  • HAI
  • MT-SP1
  • TMPRSS14
  • CAP3
• Synonyms name
  • epithin
  • matriptase
  • channel–activating protein 3
• GenBank acession
  • AF118224
• Locus
  11q24.3
• Discovery year
  1998-05-05
• Entrez gene record
  6768
• Pubmed identfication
  • 9925927
  • 10373424
• Classification
  • Type II transmembrane serine proteases
• VEGA ID
  OTTHUMG00000165768

Gene info

• Identity
  HGNC:31639
• Gene
  MIR7-2
• Long gene name
  microRNA 7-2
• Synonyms gene
  • MIRN7-2
• Synonyms
  • hsa-mir-7-2
• Locus
  15q26.1
• Discovery year
  2004-04-23
• Entrez gene record
  407044
• RefSeq identity
  • NR_029606
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:32051
• Gene
  MIR329-2
• Long gene name
  microRNA 329-2
• Synonyms gene
  • MIRN329-2
• Synonyms
  • hsa-mir-329-2
• Locus
  14q32.31
• Discovery year
  2005-07-11
• Entrez gene record
  574409
• RefSeq identity
  • NR_029968
• Classification
  • MicroRNA MIR329 family

Gene info

• Identity
  HGNC:32091
• Gene
  MIR512-2
• Long gene name
  microRNA 512-2
• Synonyms gene
  • MIRN512-2
• Synonyms
  • hsa-mir-512-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574459
• RefSeq identity
  • NR_030181
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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