0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US source) and 0.05% sodium azide
Rabbit (Oryctolagus cuniculus)
Polyclonal (rabbit origin)
Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
Western blot: 1-3ug/ml
Provided assay concentrations are suggestions only, TRH receptor antibody titration may be required for optimal results.
1X Phosphate Buffered Saline (PBS), pH 7.4
This TRH Receptor antibodyis to be used only for research purposes and not for diagnostics..
Gene ID #
This antibody was purified by Protein A method
Thyrotropin-releasing hormone (TRH) is produced by tissues of the nervous system and to a lesser degree, pancreas, testis, adrenal gland and lymphoid organs. There are two types of TRH in rodents, TRH1 and 2, but only TRH1 in humans. In cells of the nervous system, it is a neurotransmitter, acting via its receptor, TRH receptor, to stimulate phosphoinositide-specific phospholipase C, which stimulates phosphatidylinositol hydrolysis to form inositol triphosphate.
A recombinant protein fragment from the C-terminal region of TRH receptor was used as the immunogen for this antibody.
Aliquot the TRH receptor antibody and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.