TRAF1 Antibody

• Catalog number
  F43380-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TRAF1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the TRAF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This TRAF1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q13077
• Purity
  Antigen affinity
• Description
  The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene.
• Immunogen
  A portion of amino acids 55-83 from the human protein was used as the immunogen for this TRAF1 antibody.
• Storage
  Aliquot the TRAF1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRAF1  
• Gene symbol
  TRAF1
• Short name
  Anti-TRAF1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to TRAF1
• Alternative technique
  antibodies
• Alternative to gene target
  TNF receptor-associated factor 1, EBI6 and MGC:10353, TRAF1 and IDBG-83153 and ENSG00000056558 and 7185, thioesterase binding, Cytoplasm, Traf1 and IDBG-163730 and ENSMUSG00000026875 and 22029, TRAF1 and IDBG-638832 and ENSBTAG00000003012 and 540944

Gene info

• Identity
  HGNC:12031
• Gene
  TRAF1
• Long gene name
  TNF receptor associated factor 1
• Synonyms
  • EBI6
• GenBank acession
  • AK090468
• Locus
  9q33.2
• Discovery year
  1997-06-12
• Entrez gene record
  7185
• Pubmed identfication
  • 8069916
• RefSeq identity
  • NM_005658
• Classification
  • TNF receptor associated factors
• VEGA ID
  OTTHUMG00000020578

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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