STAT1 Antibody

• Catalog number
  R30581
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  STAT1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the STAT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This STAT1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P42224
• Purity
  Antigen affinity
• Description
  Chen et al.(1998) determined the crystal structure of the DNA complex of a 67-kD core fragment of the STAT1 homodimer, lacking only the N-domain and the C-terminal transcriptional activation domain, at 2.9-angstrom resolution. Phosphorylation of Signal Transducer and Activator of transcription 1 was also decreased in rheumatoid arthritis lymphocytes. It plays a key role in immunity against mycobacterial and viral infections. Activation of the Signal transducers and activators of transcription (STAT) pathway is important in fibroblast growth factor (FGF) modulation of chondrocyte proliferation and endochondral bone formation during embryogenesis.
• Immunogen
  An amino acid sequence from the C-terminus of human STAT1 (RIVGSVEFDSMMNTV) was used as the immunogen for this STAT1 antibody.
• Storage
  After reconstitution, the STAT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  STAT1  
• Gene symbol
  STAT1
• Short name
  Anti-STAT1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to STAT1
• Alternative technique
  antibodies
• Alternative to gene target
  signal transducer and activator of transcription 1, 91kDa, CANDF7 and IMD31A and IMD31B and IMD31C and ISGF-3 and STAT91, STAT1 and IDBG-77617 and ENSG00000115415 and 6772, sequence-specific DNA binding, nuclei, Stat1 and IDBG-153162 and ENSMUSG00000026104 and 20846, STAT1 and IDBG-642654 and ENSBTAG00000007867 and 510814,515988

Gene info

• Identity
  HGNC:11362
• Gene
  STAT1
• Long gene name
  signal transducer and activator of transcription 1
• Synonyms gene name
  • signal transducer and activator of transcription 1, 91kD
  • signal transducer and activator of transcription 1, 91kDa
• Synonyms
  • STAT91
  • ISGF-3
• Synonyms name
  • transcription factor ISGF-3 components p91/p84
• Locus
  2q32.2
• Discovery year
  1995-11-08
• Entrez gene record
  6772
• Pubmed identfication
  • 7885841
• RefSeq identity
  • NM_007315
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000132699
• Locus Specific Databases
  • STAT1base: Mutation registry for STAT1 deficiency
  • LRG_111

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products