SNX2 Antibody, Cy5 Conjugated
SNX2 Polyclonal Antibody, Cy5 Conjugated
Conjugated Primary Antibodies
Rabbit (Oryctolagus cuniculus)
This is a highly specific antibody against SNX2.
1ug per 1ul
KLH conjugated synthetic peptide derived from human SNX2
Gene ID number
Human, Mouse, Rat
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:16179610). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex (PubMed:17101778). The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity (PubMed:23085988). Required for retrograde endosome-to-TGN transport of TGN38 (PubMed:20138391). Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (PubMed:20604901).
This antibody was purified via Protein A.
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
TRG-9; Sorting nexin-2; Transformation-related gene 9 protein; SNX2; TRG9
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
SNX2 Antibody, Conjugated
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
sorting nexin 2 (Antibody to), cyanine 5 coupled
Alternative to gene target
sorting nexin 2, TRG-9, SNX2 and IDBG-38906 and ENSG00000205302 and 6643, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006886 and intracellular protein transport and biological process this GO :0006897 and endocytosis and biological process this GO :0010008 and endosome membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0030904 and retromer complex and cellular component this GO :0031901 and early endosome membrane and cellular component this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, phosphatidylinositol binding, this GO :0005515: protein binding and also this GO :0035091: phosphatidylinositol binding, this GO :0005515: protein binding, this GO :0035091: phosphatidylinositol binding, Cytoplasm, Snx2 and IDBG-146883 and ENSMUSG00000034484 and 67804, BT.26946 and IDBG-644960 and ENSBTAG00000025358 and 509769
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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