SLITRK2 Antibody, ALEXA FLUOR 350

  • Catalog number
    bs-11955R-A350
  • Price
    Please ask
  • Size
    100ul
  • Long name
    SLITRK2 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
  • Also known as
    Anti-SLITRK2 PAb ALEXA FLUOR 350
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 350
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    SLITRK2
  • Specificity
    This is a highly specific antibody against SLITRK2.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Subcellular location
    Extracellular
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLITRK2
  • Tested applications
    FCM, IF(IHC-P)
  • Recommended dilutions
    FCM(1:20-100), IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK2 (SLIT and NTRK-like protein 2) is a 845 amino acid single-pass type I membrane protein that contains 14 LRR (leucine-rich) repeats and is expressed in neural tissues, with highest levels found in adult cerebral cortex. Overexpression of SLITRK2 leads to inhibition of unipolar neurites in cultured cells, suggesting that it suppresses neurite outgrowth. Inhibitory activity of SLITRK2 is localized to its C-terminal intracellular domain and without this region the protein induces neurite outgrowth. Variants in the gene encoding SLITRK2 may contribute to the development of bipolar disorder, autism spectrum disorder and schizophrenia. There are two isoforms of SLITRK2 that are produced as a result of alternative splicing events.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    343nm/442nm
  • Synonyms
    CXorf2; KIAA1854; SLIK2_HUMAN; SLIT and NTRK like protein 2; SLIT and NTRK-like protein 2; SLITL1; SLITRK 2; Slitrk2.
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 350
  • French translation
    anticorps
  • Gene target
    SLITRK2  
  • Gene symbol
    SLITRK2
  • Short name
    Anti-SLITRK2
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 350
  • Alternative name
    SLITRK2 Polyclonal Antibody, ALEXA FLUOR 350
  • Alternative technique
    antibodies
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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