SIN1 Antibody

• Catalog number
  N1067-100UG
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  SIN1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat, Dog ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 1-3ug/ml
• Notes
  Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results.
• Added buffer
  1X Phosphate Buffered Saline (PBS), pH 7.4
• Intented use
  This SIN1 antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  79109
• Purity
  This antibody was purified by Protein A method
• Description
  mTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
• Immunogen
  A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.
• Storage
  Aliquot and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SIN1  
• Gene symbol
  MAPKAP1
• Short name
  Anti-SIN1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to SIN1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18752
• Gene
  MAPKAP1
• Long gene name
  MAPK associated protein 1
• Synonyms gene name
  • mitogen-activated protein kinase associated protein 1
• Synonyms
  • MGC2745
  • SIN1
  • MIP1
• Synonyms name
  • stress-activated protein kinase-interacting 1
• GenBank acession
  • M37191
• Locus
  9q33.3
• Discovery year
  2002-07-19
• Entrez gene record
  79109
• Pubmed identfication
  • 15363842
• Classification
  • MTOR complex 2
• VEGA ID
  OTTHUMG00000020683

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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