SETDB1 Antibody
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Catalog numberF40900-0.4ML
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PricePlease ask
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Size0.4 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormPurified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenSETDB1
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, ELISA
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Recommended dilutionsWestern blot: 1:1000
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NotesTitration of the SETDB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis SETDB1 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ15047
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PurityPurified
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DescriptionThe SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities.
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ImmunogenA portion of amino acids 1193-1225 from the human protein was used as the immunogen for this SETDB1 antibody.
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StorageAliquot the SETDB1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSETDB1
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Short nameAnti-SETDB1
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to SETDB1
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameSET domain bifurcated histone lysine methyltransferase 1
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Synonyms gene name
- SET domain, bifurcated 1
- SET domain bifurcated 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-07-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tudor domain containing
- Methyl-CpG binding domain containing
- SET domain containing
- Lysine methyltransferases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data