SAP97 Antibody / DLG1

• Catalog number
  R32206
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  SAP97 / DLG1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  Optimal dilution of the SAP97 antibody should be determined by the researcher.
• Intented use
  This SAP97 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q12959
• Purity
  Antigen affinity
• Description
  Disks large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a protein that in humans is encoded by the SAP97 gene. SAP97 is expressed throughout the body in epithelial cells, including the kidney and brain. There is some evidence that SAP97 regulates cell-to-cell adhesion during cell death, and may interact with HPV. In the brain, SAP97's function is involved in the trafficking of transmembrane receptors from the ER to the plasma membrane. SAP97's function has been investigated by reducing its expression by knockout or increasing its expression heterologously. Mice in which the SAP97 gene has been knocked out die perinatally, have a cleft palate, and deficiencies in renal function. Overexpression of SAP97 in mammalian neurons leads to increased synaptic strength.
• Immunogen
  Amino acids 1-165 of human SAP97 were used as the immunogen for the SAP97 antibody.
• Storage
  After reconstitution, the SAP97 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic, membrane
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SAP97   DLG1  
• Gene symbol
  DLG1, DLG1-AS1, DLGAP5
• Short name
  Anti-SAP97 / DLG1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to SAP97 / DLG1
• Alternative technique
  antibodies
• Alternative to gene target
  discs, large homolog 1 (Drosophila), dJ1061C18.1.1 and DLGH1 and hdlg and SAP-97 and SAP97, DLG1 and IDBG-71508 and ENSG00000075711 and 1739, L27 domain binding, nuclei, Dlg1 and IDBG-152959 and ENSMUSG00000022770 and 13383, DLG1 and IDBG-634119 and ENSBTAG00000020378 and

Gene info

• Identity
  HGNC:2900
• Gene
  DLG1
• Long gene name
  discs large MAGUK scaffold protein 1
• Synonyms gene name
  • discs, large homolog 1 (Drosophila)
  • discs large homolog 1, scribble cell polarity complex component
• Synonyms
  • SAP97
  • SAP-97
  • hdlg
  • DLGH1
  • dJ1061C18.1.1
• Synonyms name
  • discs large homolog 1
  • presynaptic protein SAP97
  • synapse-associated protein 97
• GenBank acession
  • U13897
• Locus
  3q29
• Discovery year
  1995-05-04
• Entrez gene record
  1739
• Pubmed identfication
  • 7937897
  • 8825652
• RefSeq identity
  • NM_004087
• Classification
  • Membrane associated guanylate kinases
  • PDZ domain containing
  • MicroRNA protein coding host genes
  • Scribble complex
• VEGA ID
  OTTHUMG00000047972

Gene info

• Identity
  HGNC:44154
• Gene
  DLG1-AS1
• Long gene name
  DLG1 antisense RNA 1
• Synonyms gene name
  • DLG1 antisense RNA 1 (non-protein coding)
• GenBank acession
  • BC039329
• Locus
  3q29
• Discovery year
  2012-06-30
• Entrez gene record
  100507086
• RefSeq identity
  • NR_038289
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000155484

Gene info

• Identity
  HGNC:16864
• Gene
  DLGAP5
• Long gene name
  DLG associated protein 5
• Synonyms gene
  • DLG7
• Synonyms gene name
  • discs, large homolog 7 (Drosophila)
  • discs, large (Drosophila) homolog-associated protein 5
  • discs large homolog associated protein 5
• Synonyms
  • KIAA0008
  • DLG1
  • HURP
• GenBank acession
  • D13633
• Locus
  14q22.3
• Discovery year
  2002-11-19
• Entrez gene record
  9787
• Pubmed identfication
  • 7584026
  • 7584028
• RefSeq identity
  • NM_014750
• VEGA ID
  OTTHUMG00000140310

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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