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RNF126 Antibody, ALEXA FLUOR 594

  • Catalog number
    bs-2125R-A594
  • Product name
    RNF126 Antibody, ALEXA FLUOR 594
  • Size
    100ul
  • Price
    333EUR
  • Supplier
    Bioss Primary Conjugated Antibodies. ALEXA FLUOR
  • Ask
  • Long name
    RNF126 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
  • Also known as
    Anti-RNF126 PAb ALEXA FLUOR 594
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 594
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    RNF126
  • Specificity
    This is a highly specific antibody against RNF126.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    80-130/313
  • Subcellular location
    Cytoplasm, Nucleus
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF126
  • Gene ID Number
    55658
  • Swiss Prot
    Q9BV68
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross-reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    E3 ubiquitin-protein ligase that regulates several biological processes through ubiquitination of various target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates. Through their polyubiquitination, may play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, FLT3, MET and CXCR4. May also be part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome. May provide the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the mislocalized proteins and their targeting to the proteasome (PubMed:24981174). May also play a role in the endosomal recycling of IGF2R, the cation-independent mannose-6-phosphate receptor (PubMed:24275455). By ubiquitinating CDKN1A/p21 and targeting it for degradation, may also promote cell proliferation (PubMed:23026136). May monoubiquitinate AICDA (PubMed:23277564).
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    590nm/617nm
  • Synonyms
    E3 ubiquitin-protein ligase RNF126; RING finger protein 126; RNF126
  • Properties
    For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR® 594
  • Conjugated
    Alexa conjugate 1
  • French translation
    anticorps
  • Gene target
  • Short name
    RNF126 Antibody,
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Label
    ALEXA FLUOR 594
  • Alternative name
    RNF126 (Antibody to), ALEXA FLUOR 594
  • Alternative technique
    antibodies
  • Ask
1. Gene info
MESH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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