Anti-PRAME Antibody

• Catalog number
  A1914-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  PRAME
• Target Alternative Name
  OIP4, preferentially expressed antigen in melanoma, CT130, PRAME, OIP-4, MAPE
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PRAME (NP_996839.1).
• Accession
  P78395
• Gene Id
  23532
• Appearance
  Liquid
• Form
  Liquid
• Formulation
  Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Purification
  Affinity purification
• Application
  Immunofluorescence (IF)
• Application And Usages
  WB 1:500 - 1:2000, IF 1:20 - 1:50
• Description
  This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  False
• Immunocytochemistry Verified
  False
• Immunofluorescence Verified
  True
• Immunoprecipitation Verified
  False
• FACS Verified
  False
• ELISA Verified
  False
• ChIP Verified
  False
• Dot Blot Verified
  False
• Flow Cytometry Verified
  False
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PRAME  
• Gene symbol
  PRAME
• Short name
  Anti-PRAME Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toPRAME (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  preferentially expressed antigen in melanoma, CT130 and MAPE and OIP-4 and OIP4, PRAME and IDBG-2240 and ENSG00000185686 and 23532, retinoic acid receptor binding, nuclei

Gene info

• Identity
  HGNC:9336
• Gene
  PRAME
• Long gene name
  PRAME nuclear receptor transcriptional regulator
• Synonyms gene
  • MAPE
• Synonyms gene name
  • preferentially expressed antigen in melanoma
• Synonyms
  • CT130
• Synonyms name
  • cancer/testis antigen 130
• GenBank acession
  • U65011
• Locus
  22q11.22
• Discovery year
  1996-06-21
• Entrez gene record
  23532
• Pubmed identfication
  • 9047241
  • 10591208
• RefSeq identity
  • NM_206953
• Classification
  • PRAME family
• VEGA ID
  OTTHUMG00000151172

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products