PP2A alpha + beta Antibody, Biotin Conjugated

• Catalog number
  bs-0029R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  PP2A alpha + beta Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  PP2A alpha + beta
• Specificity
  This is a highly specific antibody against PP2A alpha + beta.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  267-309/309
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic peptide derived from human PP-2A
• Gene ID number
  5515
• Swiss Prot
  P67775
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV4 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  RP-C; PP2Ac; PP2CA; PP2Calpha; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; PPP2CA
• Description
  The Anti-PP2A alpha + beta is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  PP2A   alpha   beta   Conjugated  
• Gene symbol
  PPP2R1B, PPP2R1A
• Short name
  Anti-PP2A alpha + beta
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-PP2A alpha + beta PAb Biotin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9303
• Gene
  PPP2R1B
• Long gene name
  protein phosphatase 2 scaffold subunit Abeta
• Synonyms gene name
  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform
  • protein phosphatase 2 regulatory subunit A, beta
• Synonyms
  • PR65B
  • PP2A-Abeta
• Synonyms name
  • PP2A-A-beta
  • protein phosphatase 2A, regulatory subunit A, beta isoform
• GenBank acession
  • AF087438
• Locus
  11q23.1
• Discovery year
  1993-01-25
• Entrez gene record
  5519
• Pubmed identfication
  • 2159327
  • 9795170
• RefSeq identity
  • NM_002716
• Classification
  • STRIPAK complex
  • Protein phosphatase 2 scaffold subunits
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000166741

Gene info

• Identity
  HGNC:9302
• Gene
  PPP2R1A
• Long gene name
  protein phosphatase 2 scaffold subunit Aalpha
• Synonyms gene name
  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
• Synonyms
  • PR65A
  • PP2A-Aalpha
  • PP2AA
• Synonyms name
  • protein phosphatase 2A, regulatory subunit A, alpha isoform
  • protein phosphatase 2, 65kDa regulatory subunit A
  • protein phosphatase 2A structural subunit A, alpha isoform
• Locus
  19q13.41
• Discovery year
  1993-01-25
• Entrez gene record
  5518
• RefSeq identity
  • NM_014225
• Classification
  • STRIPAK complex
  • Protein phosphatase 2 scaffold subunits
  • Armadillo like helical domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000137367

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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