PGGT1A Antibody, Cy3 Conjugated

  • Catalog number
    bs-9547R-Cy3
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    PGGT1A Polyclonal Antibody, Cy3 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy3
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    PGGT1A
  • Specificity
    This is a highly specific antibody against PGGT1A.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic peptide derived from human PGGT1A/FNTA
  • Gene ID number
    2339
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    512,550nm/570,615nm
  • Synonyms
    CAAX farnesyltransferase alpha subunit; Farnesyl protein transferase alpha subunit; Farnesyltransferase CAAX box alpha; Farnesyltransferase, CAAX box, alpha; FPTA; FTase alpha; GGTase I alpha; PGGT1A; Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit; Protein prenyltransferase alpha subunit repeat containing 2; PTAR2; Ras proteins prenyltransferase alpha; Ras proteins prenyltransferase subunit alpha; Type I protein geranyl geranyltransferase alpha subunit; FNTA_HUMAN.
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-PGGT1A can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.
  • Additional conjugation
    cy3 conjugation kit
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    FNTA
  • Short name
    Anti-PGGT1A
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    Cy3
  • Alternative name
    Anti-PGGT1A PAb Cy3
  • Alternative technique
    antibodies
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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