p47 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-9902R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  p47 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-p47 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  p47
• Specificity
  This is a highly specific antibody against p47.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Pleckstrin/p47
• Gene ID Number
  5341
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Platelet P47, also known as NSFL1C, UBX1, UBXD10 or UBXN2C, is a 370 amino acid protein that localizes to both the nucleus and the golgi apparatus (specifically to golgi stacks) and contains one SEP domain and one UBX domain. Functioning as part of a ternary complex with VCP (a protein involved in the heterotypic fusion of transport vesicles with their target membranes) and Syntaxin 5, p47 interacts with and reduces the ATPase activity of VCP and is required for the fragmentation of golgi stacks during mitosis and for subsequent reassembly of golgi stacks after mitosis. p47 is subject to phosphorylation during mitosis, which inhibits p47-golgi interaction and is, therefore, required for proper golgi stack formation and cisternal regrowth. Human p47 shares 89% sequence identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of p47 exist due to alternative splicing events.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  p47; Platelet 47 kDa protein; Platelet and leukocyte C kinase substrate; Platelet P47; Platelet p47 protein; Pleckstrin; PLEK; PLEK_HUMAN; FLJ27168; OTTHUMP00000159962.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-p47 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  p47  
• Gene symbol
  PLEK, NSFL1C, VCPIP1
• Short name
  Anti-p47
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  p47 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9070
• Gene
  PLEK
• Long gene name
  pleckstrin
• Synonyms
  • P47
• GenBank acession
  • X07743
• Locus
  2p14
• Discovery year
  1998-04-07
• Entrez gene record
  5341
• Pubmed identfication
  • 2897630
  • 12054651
• RefSeq identity
  • NM_002664
• Classification
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000129562

Gene info

• Identity
  HGNC:15912
• Gene
  NSFL1C
• Long gene name
  NSFL1 cofactor
• Synonyms gene name
  • NSFL1 (p97) cofactor (p47)
• Synonyms
  • dJ776F14.1
  • p47
  • UBXD10
  • UBX1
  • UBXN2C
• Synonyms name
  • SHP1 homolog (S. cerevisiae)
  • UBX domain protein 2C
• GenBank acession
  • AF112211
• Locus
  20p13
• Discovery year
  2001-06-21
• Entrez gene record
  55968
• Pubmed identfication
  • 11042152
• RefSeq identity
  • NM_016143
• Classification
  • UBX domain containing
• VEGA ID
  OTTHUMG00000031665

Gene info

• Identity
  HGNC:30897
• Gene
  VCPIP1
• Long gene name
  valosin containing protein interacting protein 1
• Synonyms gene name
  • valosin containing protein (p97)/p47 complex interacting protein 1
• Synonyms
  • VCIP135
  • KIAA1850
  • FLJ23132
  • DUBA3
• GenBank acession
  • AB058753
• Locus
  8q13.1
• Discovery year
  2005-02-22
• Entrez gene record
  80124
• Pubmed identfication
  • 11347906
  • 12509440
• Classification
  • OTU domain containing
• VEGA ID
  OTTHUMG00000164560

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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