P2Y10 Antibody

• Catalog number
  bs-12070R
• Price
  Please ask
• Size
  0.1ml

• Long name
  P2Y10 Primary Polyclonal Antibody
• Also known as
  P2Y10 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  P2Y10
• Specificity
  This is a highly specific antibody against P2Y10.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  160-210/339
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human P2Y10
• Gene ID number
  27334
• Swiss Prot
  O00398
• Tested Applications
  WB, FCM, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Nucleotides are important extracellular signaling molecules that mediate several events, such as cell proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, designated P2X and P2Y. The P2Y receptor family are G protein-coupled receptors that mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C (PLC). To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. P2Y10 (purinergic receptor P2Y, G-protein coupled, 10), also known as P2RY10, is a 339 amino acid multi-pass membrane protein that is thought to act as a receptor for purines coupled to G-proteins. P2Y10 is found at low levels in blood leukocytes and is upregulated during promyelocytic cell differentiation.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  G protein coupled purinergic receptor P2Y10; P2ry10; P2Y like receptor; P2Y purinoceptor 10; P2Y-like receptor; P2Y10; P2Y10_HUMAN; Purinergic receptor P2Y G protein coupled 10; Putative P2Y purinoceptor 10.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  P2Y10  
• Gene symbol
  P2RY10
• Short name
  Anti-P2Y10
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  P2Y10 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:19906
• Gene
  P2RY10
• Long gene name
  P2Y receptor family member 10
• Synonyms gene name
  • purinergic receptor P2Y, G-protein coupled, 10
  • purinergic receptor P2Y10
• Synonyms
  • P2Y10
• GenBank acession
  • AF000545
• Locus
  Xq21.1
• Discovery year
  2003-01-28
• Entrez gene record
  27334
• Pubmed identfication
  • 11004484
  • 9755289
• Classification
  • G protein-coupled receptors, Class A orphans
• VEGA ID
  OTTHUMG00000021896
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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