OTUD5 Antibody
-
Catalog numberN1110-25UG
-
PricePlease ask
-
Size0.025mg
-
-
CategoryAntibody
-
Concentration0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
-
FormPurified
-
ConjugationUnconjugated
-
ClonePolyclonal antibody
-
Recognised antigenOTUD5
-
Host animalRabbit (Oryctolagus cuniculus)
-
ClonalityPolyclonal (rabbit origin)
-
Species reactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
-
Tested applicationsWB
-
Recommended dilutionsWestern blot: 2-5ug/ml
-
NotesProvided assay concentrations are suggestions only, antibody titration may be required for optimal results.
-
Added buffer1X Phosphate Buffered Saline (PBS), pH 7.4
-
Intented useThis OTUD5 antibodyis to be used only for research purposes and not for diagnostics..
-
Gene ID55593
-
PurityPurified by protein A Affinity Chromatography
-
DescriptionOTUD5 (ovarian tumor domain-containing 5), also called DUBA (Deubiquitinating enzyme A), is a product of the OTUD5 gene, and a suppressor of the innate immune response via its deubiquitinating activity. The Innate immune systems provide immediate but short-lived defense against infection identified by PRRs, or pattern recognition receptors. OTUD5 cleaves the lysine-63-linked polyubiquitin chains of TRAF3, causing it to dissociate from TBK1, thereby failing to stimulate IFN type 1 production and leading to a suppressed innate immune response.
-
ImmunogenA recombinant protein fragment from the C-terminal region of human OTUD5 was used as the immunogen for this antibody.
-
StorageAliquot the antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
-
PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolOTUD5
-
Short nameAnti-OTUD5
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeRabbit IgG
-
Alternative nameAntibodies to OTUD5
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameOTU deubiquitinase 5
-
Synonyms gene name
- OTU domain containing 5
-
Synonyms
-
Locus
-
Discovery year2005-09-28
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- OTU domain containing
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data