OTUD5 Antibody

• Catalog number
  N1110-100UG
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  OTUD5
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 2-5ug/ml
• Notes
  Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
• Added buffer
  1X Phosphate Buffered Saline (PBS), pH 7.4
• Intented use
  This OTUD5 antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  55593
• Purity
  Purified by protein A Affinity Chromatography
• Description
  OTUD5 (ovarian tumor domain-containing 5), also called DUBA (Deubiquitinating enzyme A), is a product of the OTUD5 gene, and a suppressor of the innate immune response via its deubiquitinating activity. The Innate immune systems provide immediate but short-lived defense against infection identified by PRRs, or pattern recognition receptors. OTUD5 cleaves the lysine-63-linked polyubiquitin chains of TRAF3, causing it to dissociate from TBK1, thereby failing to stimulate IFN type 1 production and leading to a suppressed innate immune response.
• Immunogen
  A recombinant protein fragment from the C-terminal region of human OTUD5 was used as the immunogen for this antibody.
• Storage
  Aliquot the antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  OTUD5  
• Gene symbol
  OTUD5
• Short name
  Anti-OTUD5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to OTUD5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:25402
• Gene
  OTUD5
• Long gene name
  OTU deubiquitinase 5
• Synonyms gene name
  • OTU domain containing 5
• Synonyms
  • DKFZp761A052
  • DUBA
• Locus
  Xp11.23
• Discovery year
  2005-09-28
• Entrez gene record
  55593
• Pubmed identfication
  • 24143256
• RefSeq identity
  • NM_017602
• Classification
  • OTU domain containing
• VEGA ID
  OTTHUMG00000024130

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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