NRG1 Antibody

• Catalog number
  F52563-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  NRG1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the NRG1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This NRG1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q02297
• Purity
  Antigen affinity
• Description
  Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
• Immunogen
  This NRG1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide (human).
• Storage
  Aliquot the NRG1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NRG1  
• Gene symbol
  NRG1-IT1, NRG1, NRG1-IT3
• Short name
  Anti-NRG1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to NRG1
• Alternative technique
  antibodies
• Alternative to gene target
  neuregulin 1, ARIA and GGF and GGF2 and HGL and HRG and HRG1 and HRGA and MST131 and MSTP131 and NDF and NRG1-IT2 and SMDF, NRG1 and IDBG-16182 and ENSG00000157168 and 3084, ErbB-3 class receptor binding, nuclei, Nrg1 and IDBG-146861 and ENSMUSG00000062991 and 211323, NRG1 and IDBG-628923 and ENSBTAG00000004150 and 281361

Gene info

• Identity
  HGNC:43633
• Gene
  NRG1-IT1
• Long gene name
  NRG1 intronic transcript 1
• Synonyms gene name
  • NRG1 intronic transcript 1 (non-protein coding)
• GenBank acession
  • BC037250
• Locus
  8p12
• Discovery year
  2011-12-06
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000163966

Gene info

• Identity
  HGNC:7997
• Gene
  NRG1
• Long gene name
  neuregulin 1
• Synonyms gene
  • HGL
  • NRG1-IT2
• Synonyms gene name
  • NRG1 intronic transcript 2 (non-protein coding)
• Synonyms
  • HRG
  • NDF
  • GGF
• GenBank acession
  • L12261
• Locus
  8p12
• Discovery year
  1999-03-19
• Entrez gene record
  3084
• Pubmed identfication
  • 1350381
  • 8095334
• Classification
  • I-set domain containing
  • Neuregulins
• VEGA ID
  OTTHUMG00000163918

Gene info

• Identity
  HGNC:43635
• Gene
  NRG1-IT3
• Long gene name
  NRG1 intronic transcript 3
• Synonyms gene name
  • NRG1 intronic transcript 3 (non-protein coding)
• Locus
  8p12
• Discovery year
  2011-12-06
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000164003

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products